Production scientifique


Ayrignac X, Carra-Dallière C, Codjia P, Mouzat K, Castelnovo G, Ellie E, Etcharry-Bouyx F, Belliard S, Marelli C, Portet F, Le Ber I, Durand-Dubief F, Mathey G, Stankoff B, Dorboz I, Drunat S, Boespflug-Tanguy O, Menjot de Champfleur N, Lumbroso S, Mochel F, Labauge P. Evaluation of CSF1R-related adult onset leukoencephalopathy with axonal spheroids and pigmented glia diagnostic criteria. Eur J Neurol. 2022 Jan;29(1):329-334. 

Bauchet L, Poulen GLonjon N, Vachiery-Lahaye F, Bourinet E, Perrin FE, Hugnot JP. Isolation and culture of precursor cells from the adult human spinal cord. Methods Mol Biol. 2022;2389:103-110.

Canet G, Zub E, Zussy CHernandez C, Blaquiere M, Garcia V, Vitalis M, deBock F, Moreno-Montano M, Audinat E, Desrumaux C, Planel E, Givalois L*, Marchi N*. Seizure activity triggers tau hyperphosphorylation and amyloidogenic pathways. Epilepsia 2022 Apr;63(4):919-935.

Canet GZussy CHernandez CChevallier N, Marchi N, Desrumaux CGivalois L. Chronic glucocorticoids consumption triggers and worsens experimental Alzheimer's disease-like pathology by detrimental immune-modulations. Neuroendocrinology 2022 doi: 10.1159/000521559

Caporali A, Garcia J, Couppié É, Poniakina S, Barbieri M, Bonnet F, Camarda CG, Cambois E, Hourani I, Korotkova D, Meslé F, Penina O, Robine JM, Sauerberg M, Torres C. The demography of COVID-19 deaths database, a gateway to well-documented international data. Sci Data. 2022 Mar 22;9(1):93.

Crouzier L, Danese A, Yasui Y, Richard EM, Liévens JC, Patergnani S, Couly S, Diez C, Denus M, Cubedo N, Rossel M, Thiry M, Su TP, Pinton P, Maurice T, Delprat B. Activation of the sigma-1 receptor chaperone alleviates disorders of Wolfram syndrome by restoring ER-mitochondrion signaling. Science Transl Med 2022 Feb 9;14(631).

Crouzier LRichard EMDiez CAlzaeem HDenus MCubedo N, Delaunay T, Glendenning E, Baxendale S, Liévens JC, Whitfield TT, Maurice TDelprat B. Morphological, behavioral and cellular analyses revealed different phenotype in Wolfram syndrome wfs1a and wfs1b zebrafish mutant lines. Hum Mol Genet. 2022 Mar 21:ddac065.

Crouzier L, Richard EM, Diez C, Denus M, Peyrel A, Alzaeem H, Cubedo N, Delaunay T, Maurice T, Delprat B. NCS1 overexpression restored mitochondrial activity and behavioral alterations in a zebrafish model of Wolfram syndrome. Mol Therapy, 2022 in press.

Hofmann J, Spatz P, Walther R, Gutmann M, Maurice T, Decker M. Synthesis and biological evaluation of flavonoid-cinnamic acid amide hybrids with distinct activity against neurodegeneration in vitro and in vivo. Chem Eur J. 2022; in press.

Lebart MC, Trousse F, Valette G, Torrent J, Denus M, Mestre-Frances N, Marcilhac A. Reg-1α, a New Substrate of Calpain-2 Depending on Its Glycosylation Status. Int J Mol Sci 2022, 23, 8591.

Martin P, Maurice T, Gammaitoni A, Farfel G, Boyd B, Galer B. Fenfluramine modulates the anti-amnesic effects induced by sigma-1 receptor agonists and neuro(active)steroids in vivo. Epilepsy Behav, 2022 Feb;127:108526.

Nasri A, Lafon PA, Mezni A, Clair P, Cubedo N, Mahmoudi E, Beyrem H, Rossel MPerrier V. Developmental exposure to the A6-pesticide causes changes in tyrosine hydroxylase gene expression, neurochemistry, and locomotors behavior in larval zebrafish. Toxicol Mech Methods. 2022 Apr 17:1-11.

Rochat C, Bernard-Marissal N, Källstig E, Pradervand S, Perrin FE, Aebischer P, Raoul C, Schneider BL. Astrocyte-targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast-fatigable motor units in a mouse model of amyotrophic lateral sclerosis. Glia. 2022 May;70(5):842-857.

Scheiner M, Sink A, Hoffmann M, Vrigneau C, Endres E, Carles A, Sotriffer C, Maurice T, Decker M. Photoswitchable pseudo-irreversible butyrylcholinesterase inhibitors allow optical control of inhibition in vitro and enable restoration of cognition in an Alzheimer's disease mouse model upon irradiation. J Am Chem Soc. 2022 Feb 23;144(7):3279-3284.

Zussy C, Rijo J, Urgin TOtaegui L, Vigor C, Acar N, Canet GVitalis M, Morin F, Planel E, Oger C, Durand T, Rajshree SL, Givalois L, Devarajan PV, Desrumaux C. Intranasal administration of nanovectorized docosahexaenoic acid (DHA) improves cognitive function in two complementary mouse models of Alzheimer’s disease. Antioxidants 2022, 11, 838.

Wang SM, Wu HE, Geva M, Hayden M, Maurice T, Cozzolino M, Su TP. Nucleoporin POM121 signals TFEB-mediated autophagy via activation of sigma-1 receptor by pridopidine in NSC34 model of C9ALS/FTD. Autophagy. 2022; in press.


Abatematteo FS, Mosier PD, Niso M, Brunetti L, Berardi F, Loiodice F, Contino M, Delprat B, Maurice T, Laghezza A, Abate C. Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect. Eur J Med Chem. 2021 Dec 3;228:114038.

Barbereau CCubedo NMaurice TRossel M. Zebrafish models to study new pathways in tauopathies. Int J Mol Sci. 2021;22:4626.

Bassani S, van Beelen E, Rossel M, Voisin N, Morgan A, Arribat Y, Chatron N, Chrast J, Cocca M, Delprat B, Faletra F, Giannuzzi G, Guex N, Machavoine R, Pradervand S, Smits JJ, van de Kamp JM, Ziegler A, Amati F, Marlin S, Kremer H, Locher H, Maurice T, Gasparini P, Girotto G, Reymond A. Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss. Hum Mol Genet. 2021 Sep 15;30(19):1785-1796.

Canouï-Poitrine F, Rachas A, Thomas M, Carcaillon-Bentata L, Fontaine R, Gavazzi G, Laurent M, Robine JM. Magnitude, change over time, demographic characteristics and geographic distribution of excess deaths among nursing home residents during the first wave of COVID-19 in France: a nationwide cohort study. Age Aging. 2021;in press.

Cahu M, Ali LMA, Sene S, Long J, Camerel F, Ciancone M, Salles F, Chopineau J, Devoisselle JM, Felix G, Cubedo N, Rossel M, Guari Y, Bettache N, Larionova J, Gary-Bobo M. A rational study of the influence of Mn2+-insertion in Prussian blue nanoparticles on their photothermal properties. J Mater Chem B2021 Dec 8;9(47):9670-9683.

Cecon E, Lhomme T, Maurice T, Luka M, Chen M, Silva A, Wauman J, Zabeau L, Tavernier J, Prévot V, Dam J, Jockers R. Amyloid Beta Peptide Is an Endogenous Negative Allosteric Modulator of Leptin Receptor. Neuroendocrinology. 2021;111(4):370-387. 

Chevreau R, Ghazale H, Ripoll C, Chalfouh C, Delarue Q, Hemonnot-Girard AL, Mamaeva D, Hirbec H, Rothhut B, Wahane S, Perrin FE, Noristani HN, Guerout N, Hugnot JP. RNA profiling of mouse ependymal cells after spinal cord injury identifies the oncostatin pathway as a potential key regulator of spinal cord stem cell fate. Cells. 2021 Nov 27;10(12):3332.

Couly SCarles ADenus M, Benigno-Anton L, Maschat FMaurice T. Exposure of R6/2 mice in an enriched environment augments P42 therapy efficacy on Huntington's disease progression. Neuropharmacology. 2021 Mar 15;186:108467. doi: 10.1016/j.neuropharm.2021.108467

Couly S, Denus M, Bouchet M, Rubinstenn G, Maurice T. Anti-Amnesic and Neuroprotective Effects of Fluoroethylnormemantine in a Pharmacological Mouse Model of Alzheimer's Disease. Int J Neuropsychopharmacol. 2021 Feb 15;24(2):142-157. 

Crouzier L, Denus M, Richard EM, Tavernier A, Diez C, Cubedo N, Maurice T, Delprat B. Sigma-1 Receptor Is Critical for Mitochondrial Activity and Unfolded Protein Response in Larval Zebrafish. Int J Mol Sci. 2021 Oct 13;22(20):11049.

Crouzier L, Richard EM, Sourbron J, Lagae L, Maurice T, Delprat B. Use of zebrafish models to boost research in rare genetic diseases. Int J Mol Sci. 2021 Dec 12; 22:13356.

Crouzier LDiez C, Richard EM, Cubedo NBarbereau CRossel M, Delaunay T, Maurice TDelprat B. Loss of Pde6a induces rod outer segment shrinkage and visual alterations in pde6aQ70X mutant zebrafish, a relevant model of retinal dystrophy. Front Cell Dev Biol. 2021

Forner-Piquer I, Klement W, Gangarossa G, Zub E, de Bock F, Blaquiere M, Maurice T, Audinat E, Faucherre A, Lasserre F, Ellero-Simatos S, Gamet-Payrastre L, Jopling C, Marchi N. Varying modalities of perinatal exposure to a pesticide cocktail elicit neurological adaptations in mice and zebrafish. Environ Pollut. 2021 Jun 1;278:116755.

Garcia J, Torres C, Barbieri M., Cambois E, Camarda CG, Caporali A, Meslé F, Poniakina S, Robine JM. Differences in COVID-19 Mortality: the implications of imperfect and diverse data collection systems. Population-E. 2021;76(1):035−072. 

Gautier T, Deckert V, Nguyen M, Desrumaux C, Masson D, Lagrost L. New therapeutic horizons for plasma phospholipid transfer protein (PLTP): Targeting endotoxemia, infection and sepsis. Pharmacol Ther. 2021 Dec 30;236:108105.

He F, Chou CJ, Scheiner M, Poeta E, Yuan Chen N, Gunesch S, Hoffmann M, Sotriffer C, Monti B, Maurice T, Decker M. Melatonin- and ferulic acid-based HDAC6 selective inhibitors exhibit pronounced immunomodulatory effects in vitro and neuroprotective effects in a pharmacological Alzheimer's disease mouse model. J Med Chem. 2021 Apr 8;64(7):3794-3812.

Hemonnot-Girard AL, Valverde AJ, Hua J, Delaygue C, Linck N, Maurice T, Rassendren F, Hirbec H. Analysis of CX3CR1 haplodeficiency in male and female APPswe/PSEN1dE9 mice along Alzheimer disease progression. Brain Behav Immun. 2021 Jan;91:404-417.

Jamoussi Y, Zaiter T, Desrumaux C, Acar N, Pellequer Y, Béduneau A. Investigation of the spontaneous nanoemulsification process with medium- and long-chain triglycerides. Colloids Surf B Biointerfaces. 2021 Jan;197:111432.

Lattard A, Poulen G, Bartolami SGerber YNPerrin FENegative impact of Sigma-1 receptor agonist treatment on tissue integrity and motor function following spinal cord injuryFront Neuroanat Neuropharmacol. 2021, 12:614949.

Legrand A, Pujol C, Durand CM, Mesnil A, Rubera I, Duranton C, Zuily S, Sousa AB, Renaud M, Boucher JL, Pietrancosta N, Adham S, Orssaud C, Marelli C, Casali C, Ziccardi L, Villain N, Ewenczyk C, Durr A, Mignot C, Stevanin G, Billon C, Hureaux M, Jeunemaitre X, Goizet C, Albuisson J. Pseudoxanthoma elasticum overlaps hereditary spastic paraplegia type 56. J Intern Med. 2021 May;289(5):709-725.

Lievens JC, Maurice T. Sigma-1 receptor: culprit and rescuer in motor neuron diseases. Neural Regen Res. 2021 Jan;16(1):106-107.

Maurice T. Bi-phasic dose response in the preclinical and clinical developments of sigma-1 receptor ligands for the treatment of neurodegenerative disorders. Expert Opin Drug Discov. 2021 Apr;16(4):373-389.

Montaut S, Diedhiou N, Fahrer P, Marelli C, Lhermitte B, Robelin L, Vincent MC, Corti L, Taieb G, Gebus O, Rudolf G, Tarabeux J, Dondaine N, Canuet M, Almeras M, Benkirane M, Larrieu L, Chanson JB, Nadaj-Pakleza A, Echaniz-Laguna A, Cauquil C, Lannes B, Chelly J, Anheim M, Puccio H, Tranchant C. Biallelic RFC1-expansion in a French multicentric sporadic ataxia cohort. J Neurol. 2021 Mar 5.

Moutin E, Sakkaki S, Compan V, Bouquier N, Giona F, Areias J, Goyet E, Hemonnot-Girard AL, Seube V, Glasson B, Benac N, Chastagnier Y, Raynaud F, Audinat E, Groc L, Maurice T, Sala C, Verpelli C, Perroy J. Restoring glutamate receptosome dynamics at synapses rescues autism-like deficits in Shank3-deficient mice. Mol Psychiatry. 2021 

Nakanishi Y, Tsugihashi Y, Akahane M, Noda T, Nishioka Y, Myojin T, Kubo S, Higashino T, Okuda N, Robine JM, Imamura T. Comparison of Japanese Centenarians' and Noncentenarians' Medical Expenditures in the Last Year of Life. JAMA Netw Open. 2021 Nov 1;4(11):e2131884.

Nasri A, Mezni A, Lafon PA, Wahbi A, Cubedo N, Clair P, Harrath AH, Beyrem H, Rossel M, Perrier V. Ethinylestradiol (EE2) residues from birth control pills impair nervous system development and swimming behavior of zebrafish larvae. Sci Total Environ. 2021 May 20;770:145272.

Patergnani S, Marchi S, Delprat B, Wieckowski MR. Editorial: Organelles Relationships and Interactions: A Cancer Perspective. Front Cell Dev Biol. 2021 Apr 8;9:678307. 

Perez JCPGerber YNPerrin FE (2021).Dynamic diversity of glial response among species in spinal cord injury. Front Aging Neurosci, in press.

Poulen GAloy A, Bringuier CMestre-Francés  N, Artus E, Cardoso M, Perez JC, Goze-Bac CLonjon N,  Boukhaddaoui H, Gerber YNPerrin FEInhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates Theranostics 2021, 11: 8640-59.

Poulen GBartolami SNoristani HNPerrin FEGerber YN. Unlike brief inhibition of microglia proliferation after spinal cord injury, long-term treatment does not improve motor recovery. Brain Sci. 2021 Dec 13;11(12):1643.

Poulen GGerber YNPerez JC, Oubarrahou M, Lonjon N , Vachiery-Lahaye F, Boukhaddaoui H, Perrin FCoherent anti-stokes Raman scattering microscopy: a label free method to compare spinal cord myelin in different species.Front Phys9:6656650.

Quijal-Zamorano M, Martinez-Solanas E, Achebak H, Petrova D, Robine JM, Herrmann FR, Rod. X, Ballester J. Seasonality reversal of temperature attributable mortality projections due to previously unobserved extreme heat in Europe. Lancet Planet Health. 2021 Sep;5(9):e573-e575.

Ravel JM, Benkirane M, Calmels N, Marelli C, Ory-Magne F, Ewenczyk C, Halleb Y, Tison F, Lecocq C, Pische G, Casenave P, Chaussenot A, Frismand S, Tyvaert L, Larrieu L, Pointaux M, Drouot N, Bossenmeyer-Pourié C, Oussalah A, Guéant JL, Leheup B, Bonnet C, Anheim M, Tranchant C, Lambert L, Chelly J, Koenig M, Renaud M. Expanding the clinical spectrum of STIP1 homology and U-box containing protein 1-associated ataxia. J Neurol. 2021 May;268(5):1927-1937.

Scheiner M, Hoffmann M, He F, Poeta E, Chatonnet A, Monti B, Maurice T, Decker M. Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model. J Med Chem. 2021 Jul 8;64(13):9302-9320. 

Verkhratsky A, Dayanithi G. When day meets night: Subsiding calcium signalling translates daylight into new neurones. Cell Calcium. 2021 May;95:102385.

Wang Y, Lafon PA, Salvador-Prince L, Gines AR, Trousse F, Torrent J, Prevostel C, Crozet C, Liu J, Perrier V. Prenatal exposure to low doses of fungicides corrupts neurogenesis in neonates. Environ Res. 2021 Apr;195:110829.


Barbereau C, Yehya A, Silhol M, Cubedo N, Verdier JM, Maurice T,Rossel M (2020) Neuroprotective Brain-Derived Neurotrophic Factor signaling in the TAU-P301L tauopathy zebrafish model. Pharmacological Research 158:104865.

Canet G, Pineau F, Zussy CHernandez C, Hunt H, Chevallier NPerrier VTorrent J, Belanoff JK, Meijer OC, Desrumaux CGivalois L (2020) Glucocorticoid receptors signaling impairment potentiates amyloid-β oligomers-induced pathology in an acute model of Alzheimer’s disease. The FASEB Journal 34:1150–1168

Couly S, Khalil B, Viguier V, Roussel J, Maurice TLiévens JC (2020) Sigma-1 receptor is a key modulator in amyotrophic lateral sclerosis. Hum Mol Genet 29:529-540

Delprat B, Crouzier L, Su TP, Maurice T (2020) At the Crossing of ER Stress and MAMs: A Key Role of Sigma-1 Receptor? Adv Exp Med Biol 1131:699-718

Dibakou SE, Souza A, Boundenga L, Givalois L, Mercier-Delarue S, Simon F, Prugnolle F, Huchard E, Charpentier MJ (2020) Ecological, parasitological and individual determinants of plasma neopterin levels in a natural mandrill population. Int J Parasitol Parasites Wildl 11:198-206

Fritz R, Zimmermann E, Picq J, Lautier C, Meier M, Kästner S, Schmidtke D (2020) Sex-specific patterns of age-related cerebral atrophy in a non-human primate Microcebus murinus. Neurobiology of Aging (in press)

Lafon PA, Wang Y, Arango-Lievano M, Torrent J, Salvador-Prince L, Mansuy M, Mestre-Francès N, Givalois L, Liu J, Mercader JV, Jeanneteau F, Desrumaux C, Perrier V (2020) Fungicide residues exposure and β-amyloid aggregation in a mouse model of Alzheimer's disease. Environ Health Perspect 128:17011

Lee PT, Liévens JC, Wang SM, Chuang JY, Khalil B, Wu HE, Chang WC, Maurice T, Su TP (2020) Sigma-1 receptor chaperones rescue nucleocytoplasmic transport deficit seen in cellular and Drosophila ALS/FTD models. Nat Commun 11:5580

Liévens JC, Maurice T(2020) Sigma-1 receptor: Culprit and rescuer in motor neuron diseases. Neural Regeneration Research (in press)

Paschon V, Fernandes Correia F, Cintra Morena B, Allisson da Silva V, Bispo dos Santos G, Carlan da Silva MC, Fogaça Cristante A, Willerth SF,  Perrin FE, Hiroaki Kihara (2020). CRISPR, prime editing, optogenetics and DREADDs: new therapeutic approaches provided by emerging technologies in the treatment of spinal cord injury. Mol Neurobiol 57:2085-2100

Puighermanal E, Castell L, Esteve-Codina A, Melser S, Kaganovsky K, Zussy C, Boubaker-Vitre J, Gut M, Rialle S, Kellendonk C, Sanz E, Quintana A, Marsicano G, Martin M, Rubinstein M, Girault JA, Ding JB, Valjent E (2020) Nat Commun 11: 1957

Schmidtke D,  Zimmermann E, Trouche S, Fontès P, Verdier  JM, Mestre-Francés N (2020) Linking cognition to age and amyloid-ß burden in the brain of a non-human primate (Microcebus murinus). Neurobiology of Aging  (in press)

Varilh MAcquatella-Tran Van Ba ISilhol M, Nieto-Lopez F,  Moussaed M, Lebart MC, Bovolenta P, Verdier JMRossel MMarcilhac A, Trousse F (2020). Reg-1α promotes differentiation of cortical progenitors via its N-terminal active domain. Front Cell Dev Biol, 8:681


Akbaraly T, Miot S , Baghdadli A (2019) Nutritional Epidemiology Research in the Field of Autism Spectrum Disorders–A Review. Neuropsychiatry (in press)

Akbaraly TN, Singh-Manoux A, Dugravot A, Brunner EJ, Kivimaki M, Sabia S (2019) Association of Midlife Diet With Subsequent Risk for Dementia. Jama 321:957-968.

Arribat Y, Mysiak KS, Lescouzères L, Boizot A, Ruiz M,  Rossel M, Bomont P (2019) Mutations in the Gigaxonin-E3 ligase impede the initiation of Shh signaling to cause Giant Axonal Neuropathy. J Clin Invest (in press)

Baghdadli A, Miot S, Rattaz C, Akbaraly TN, Geoffray M-M, Michelon C, Loubersac J, Traver S, Mortamais M, Sonié S, Pottelette J, Robel L, Speranza M, Vesperini S, Maffre T, Falissard B, Picot M-C (2019) Investigating the natural history and prognostic factors of ASD in children: the multicEntric Longitudinal study of childrEN with ASD - the ELENA study protocol. BMJ Open 9: e026286

Brodoline A, Rawat N, Alexandre D, Cubedo N, Gross M (2019) 4D compressive sensing holographic imaging of small moving objects with multiple illuminations. Applied Optics 58: G127-G134.

Brodoline A, Rawat N, Alexandre D, Cubedo N, Gross M (2019) 4D compressive sensing holographic imaging of small moving objects. Optics Letters 44, 2827.

Chudinova A, Rossel M, Vergunst AC, Le Masson G, Camu W, Raoul C, Lumbroso S, Mouzat K (2019) Theme 4 In vivo experimental models. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20: 160–187

Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze J-F, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen L-P, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine J-M, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM (2019) A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun 10: 3669

Canet GHernandez CZussy CChevallier NDesrumaux C,Givalois L(2019) Is AD a stress-related disorder? Focus on the HPA axis and its promising therapeutic targets.Frontiers in Aging Neuroscience 11:269.

Ghazale H, Ripoll C, Leventoux N, Jacob J, Azar S, Mamaeva D, Glasson Y , Calvo CF, Thomas JL, Meneceur S, Lallemand Y, Rigau V, Perrin FENoristani HN, Rocamonde B, Huillard E, Bauchet L, Hugnot JP (2019). RNA profiling of the human and mouse spinal cord stem cell niches reveals an embryonic-like dorsal-ventral regionalization with MSX1+ roof-plate-derived cells. Stem Cell Reports, (in press).

Filip S, Mokrý J, Forostyak O, Dayanithi G (2019) Analysis of Ca2+ signaling mechanisms - our experience on the intercellular communication in muscle remodeling. Physiol Res. (In press).

Filip S, Mokrý J, Forostyak O, Dayanithi G (2019) The extracellular matrix and Ca2+ signaling mechanisms. Physiol Res. (in press).

Folio DM, Aars J, Gimenez O, Derocher AE, Wiig Ø, Cubaynes S (2019) How many cubs can a mum nurse? Maternal age and size influence litter size in polar bears. Biol. Lett. 15: 20190070

Gunesch S, Kiermeier C, Hoffmann M, Fischer W, Pinto A, Maurice T, Maher P, Decker M (2019) 7-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory in vivo. Redox Biol (in press)

Haydar S, Grigorescu F, Vintilă M, Cogne Y, Lautier C, Tutuncu Y, Brun JF, Robine JM, Pugeat M, Normand C, Poucheret P, Gheorghiu ML, Georgescu C, Badiu C, Băculescu N, Renard E, Ylli D, Badiou S, Sutra T, Cristol JP, Mercier J, Gomis R, Macias JM, Litvinov S, Khusnutdinova E, Poiana C, Pasquali R, Lauro D, Sesti G, Prudente S, Trischitta V, Tsatsoulis A, Abdelhak S, Barakat A, Zenati A, Ylli A, Satman I, Kanninen T, Rinato Y, Missoni S (2019) Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation. PLoS ONE 14: e0214122

Hoffmann M, Stiller C, Endres E, Scheiner M, Gunesch S, Sotriffer C, Maurice T, Decker M (2019) Tunable duration of action of highly selective BChE inhibitors by chemical modification of transferable carbamate moieties lead to pronounced neuroprotective effects in an Alzheimer´s disease mouse model. J Med Chem 62: 9116-9140.

Kayano T, Sasaki Y, Kitamura N, Harayama N, Moriya T, Dayanithi G, Verkhratsky A, Shibuya I (2019) Persistent Na+ influx drives L-type channel resting Ca2+ entry in rat melanotrophs. Cell Calcium 79:11-19.

Lalut J, Santoni G, Karila D, Lecoutey C, Davis A, Nachon F, Sillman I, Sussman J, Weik M, Maurice T, Dallemagne P, Rochais C (2019) Synthesis, evaluation and structural characterization of novel multitarget directed ligand targeting acetylcholinesterase and sigma-1 receptors of potential interest for Alzheimer's disease treatment. Eur J Med Chem 162: 234-248.

Laroui N, Cubedo N, Rossel M, Bettache N (2019) Improvement of cell penetrating peptide for efficient siRNA targeting of tumor xenografted in zebrafish embryos. Advanced Therapeutics (in press).

Lasbleiz C, Mestre-Francés N, Devau G, Luquin MR, Tenenbaum L, Kremer EJ, Verdier JM (2019) Combining gene transfer and nonhuman primates to better understand and treat Parkinson’s disease. Front Mol Neurosci.12:10

Lassale C, Batty GD, Baghdadli A, Jacka F, Sánchez-Villegas A, Kivimaki M, Akbaraly TN, Batty GD (2019) Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies. Molecular Psychiatry 24: 965–986

Lassale C, Batty GD, Steptoe A, Cadar D, Akbaraly TN, Kivimaki M, Zaninotto P (2019) Association of 10-Year C-Reactive Protein Trajectories With Markers of Healthy Aging: Findings From the English Longitudinal Study of Aging. The journals of gerontology. Series A, Biological sciences and medical sciences74:195-203.

Lepvrier E, Thomas D, Garnier C (2019) Hsp90 Quaternary Structures and the Chaperone Cycle: Highly Flexible Dimeric and Oligomeric Structures and Their Regulation by Co-Chaperones. Current Proteomics 16: 5–11

Manzo E, Lorenzini I, Barrameda D, O'Conner AG, Barrows JM, Starr A, Kovalik T, Rabichow BE, Lehmkuhl EM, Shreiner DD, Joardar A, Liévens JC, Bowser R, Sattler R, Zarnescu DC. (2019) Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS. Elife8 : e45114.

Marelli C, Salsano E, Politi LS, Labauge P (2019) Spinal cord involvement in adult-onset metabolic and genetic diseases. Journal of Neurology, Neurosurgery and Psychiatry 90: 211–218

Maurice T, Volle JN, Strehaiano M, Crouzier L, Pereira C, Kaloyanov N, Virieux D, Pirat JL (2019) Neuroprotection in non-transgenic and transgenic mouse models of Alzheimer's disease by positive modulation of σ1 receptors. Pharmacol Res 144: 315-330.

Noristani HN, Perrin FE (2019). Use of longitudinal magnetic resonance imaging in preclinical models of spinal cord injury. Editorial Neural Regeneration Research, 14: 771-772.

Nusselder WJ, Cambois E, Wapperom D, Meslé F, Looman C, Yokota RTC, Van Oyen H, Jagger C, Robine J-M (2019) Women’s excess unhealthy life years: disentangling the unhealthy life years gap. European Journal of Public Health 29: 914-919

Pagnamenta AT, Heemeryck P, Martin HC, Bosc C, Peris L, Uszynski I, Gory-Fauré S, Couly S, Deshpande C, Siddiqui A, Elmonairy AA, Jayawant S, Murthy S, Walker I, Loong L, Bauer P, Vossier F, Denarier E, Maurice T, Barbier EL, Deloulme JC, Taylor JC, Blair EM, Andrieux A, Moutin MJ (2019) Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice. Hum Mol Genet (in press).

Rama R, Garzón F, Rodríguez Cruz Y, Maurice T, García Rodríguez JC (2019) Neuroprotective effect of NeuroEPO in neurodegenerative disease: “Alea jacta est”. Neural Regener Res 14: 1519-1521.

Recchia D, Baghdadli A, Lassale C, Brunner E, Verdier JM, Kivimaki M, Akbaraly  (2019). Associations between long-term adherence to healthy diet and recurrent depressive symptoms in Whitehall II Study. European journal of nutrition (in press)

Scheiner M, Gunesch S, Dolles D, Hoffmann M, Oliviero M, Nabissi M, Naldi M, Bartolini M, Petralla S, Poeta E, Monti B, Falkeis C, Vieth M, Maurice T, Decker M (2019) Dual-acting cholinesterase-human cannabinoid receptor 2 ligands show pronounced neuroprotection in vitro, and overadditive and disease-modifying neuroprotective effects in vivo. J Med Chem. 62: 9078-9102.

Torrent J, Martin D, Igel-Egalon A, Beringue VV and Rezaei H (2019) High-Pressure Response of Amyloid Folds. Viruses 11: pii: E202

Trousse F, Jemli A, Silhol M, Garrido E, Crouzier L, Naert G, Maurice T, Rossel M (2019) Knockdown of CXCL12 /CXCR7 chemokine pathway results in learning deficits and neural progenitors maturation failure in mice. Brain Behav Immun. 80: 697-710.

Vavers E, Zvejniece L, Maurice T, Dambrova M (2019) Allosteric modulators of sigma-1 receptor: a review. Front Pharmacol 10: 223.

Zub E, Canet GGarbelli R, Blaquiere M,Rossini L, Pastori C, Sheikh M, Reutelingsperger C, Klement W, de Bock F, Audinat E, Givalois L, Solito E, MarchiN (2019) The ANXA1-GR pathway is a pathological player and a potential pharmacological target in epilepsy. FASEB Journal 33:13998-14009


Akbaraly T, Sexton C, Zsoldos E, Mahmood A, Filippini N, Kerleau C, Verdier JM, Virtanen M, Gabelle A, Ebmeier KP, Kivimaki M (2018). Association of long-term diet quality with hippocampal volume: longitudinal cohort study. The American journal of medicine 131:1372-1381.

Akbaraly T, Wurtz P, Singh-Manoux A, Shipley MJ, Haapakoski R, Lehto M, Desrumaux C, Kahonen M, Lehtimaki T, Mikkila V, Hingorani A, Humphries SE, Kangas AJ, Soininen P, Raitakari O, Ala-Korpela M, Kivimaki M (2018). Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies. Scientific reports. 8:8620.

Audo R, Deckert V, Daien CI, Che H, Elhmioui J, Lemaire S, Pais de Barros JP, Desrumaux C, Combe B, Hahne M, Lagrost L, Morel J (2018) PhosphoLipid transfer protein (PLTP) exerts a direct pro-inflammatory effect on rheumatoid arthritis (RA) fibroblasts-like-synoviocytes (FLS) independently of its lipid transfer activity. PLoS One 13: e0193815.

Assmann KE, Adjibade M, Shivappa N, Hebert JR, Wirth MD, Touvier M, Akbaraly T, Hercberg S, Galan P, Julia C, Kesse-Guyot E (2018). The Inflammatory Potential of the Diet at Midlife Is Associated with Later Healthy Aging in French Adults. The Journal of nutrition148:437-444.

Azria D, Blanquer S, Verdier JM, Belamie E (2018) Nanoparticles as contrast agents for brain nuclear magnetic resonance imaging in Alzheimer’s disease diagnosis. Journal of Materials Chemistry B (In press)

Canet GChevallier NPerrier VDesrumaux C, Givalois L (2018).  Targeting glucocorticoid receptors: a new avenue for Alzheimer's disease therapy. In; "Pathology, Prevention and Therapeutics of Neurodegenerative Disease". Ed. Springer Nature, Chap. 15, 173-183.

Canet GChevallier N, Zussy CDesrumaux C, Givalois L (2018). Central role of glucocorticoid receptors in Alzheimer’s disease and depression. Frontiers in Neuroscience 12:739. doi: 10.3389/fnins.2018.00739

Canet G, Dias C, Gabelle A, Simonin Y, Gosselet F, Marchi N, Makinson A, Tuaillon E, Van de Perre P, Givalois L, Salinas S (2018). HIV Neuroinfection and Alzheimer’s Disease: Similarities and Potential Links? Frontiers in Cellular Neuroscience 12: 307;10.3389/fncel.2018.00307

Charpentier MJ, Givalois L, Faurie C, Soghessa O, Simon F, Kappeler PM (2018) Seasonal variation in glucocorticoid production in mandrills depends on a suite of small-magnitude effects. American Journal of Physical Anthropology 165:20-33.

Couly S, Paucard A, Bonneaud N, Maurice T, Benigno L, Jourdan C, Cohen-Solal C, Vignes M, Maschat F (2018) Improvement of BDNF signalling by P42 peptide in Huntington's disease. Hum Mol Genet 27:3012-3028.

Crouzier LGilabert D, Rossel MTrousse FMaurice T (2018) Topographical memory analyzed in mice using the Hamlet Test, a novel complex maze. Neurobiol Learn Mem 149:118-134.

Crouzier LMaurice T (2018) Assessment of topographic memory in mice in a complex environment using the Hamlet test. Current Protoc Mouse Biol (in press)

Dayanithi G, Forostyak O, Forostyak S, Kayano T, Ueta Y, Verkhratsky A (2018).  Vasopressin and oxytocin in sensory neurones: expression, exocytotic release and regulation by lactation. Scientific Reports 30; 8:13084.

Delprat BMaurice T, Delettre C (2018) Wolfram syndrome: MAMs’ connection? Cell Death Dis 9:364.

Desrumaux C, Lagrost L (2018). Plasma phospholipid transfer protein (PLTP) as an emerging determinant of the audemars piguet replica adaptive immune response. Cell Mol Immunol, doi: 10.1038/s41423-018-0036-9.
Desrumaux C, Mansuy M, Lemaire S, Przybilski J, Le Guern N, Givalois L, Lagrost L (2018) Brain Vitamin E Deficiency During Development Is Associated With Increased Glutamate Levels and Anxiety in Adult Mice. Front Behav Neurosci 12:310

Dolles D, Hoffmann M, Oliviero M, Möller J, Santoni G, Chatonnet A, Lohse M, Wittmann HJ, Strasser A, Nabissi M, Maurice T, Decker M (2018) Structure-activity relationships and computational investigations into the development of potent and balanced dual-acting butyrylcholinesterase inhibitors and hCB2R ligands with pro-cognitive in vivo profile. J Med Chem ( in press)

Gerber YN, *Saint-Martin GP, Bringuier C, Bartolami S, Goze-Bac C, Noristani HN, Perrin FE (2018). Reduction of microglia proliferation through CSFR1 targeting improves motor recovery following spinal cord injury. Frontiers in Cellular Neurosciences, 12:368.

Goguadze N, Zhuravliova E, Morin D, Mikeladze D, Maurice T (2018) Sigma-1 receptor agonists induce oxidative stress in mitochondria and enhance complex I activity in physiological condition, but protect against pathological oxidative stress. Neurotox Res. (in press).

Herr M, Jeune B, Fors S, Andersen-Ranberg K, Ankri J, Arai Y, Cubaynes S, Santos-Eggimann B, Zekry D, Parker M, Saito Y (2018). Frailty and Associated Factors among Centenarians in the 5-COOP Countries. Gerontology, 1-11. doi: 10.1159/000489955

Lafon PA, Imberdis T, Wang YY, Torrent J, Robitzer M, Huetter E, Alvarez-Martinez MT, Chevallier N, Givalois L, Desrumaux C, Liu JF, Perrier V (2018) Low doses of bioherbicide favours prion aggregation and propagation in vivo. Scientific Reports 8:8023..

Lassale C, Batty DG, Baghdadli A, Jacka F, Sanchez-Villegas A, Kivimaki M, Akbaraly T (2018). Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies. Molecular Psychiatry Sept 26.

Lassale C, Batty DG, Baghdadli A, Jacka F, Sanchez-Villegas A, Kivimaki M, Akbaraly T (2018). Correction: Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies. Molecular Psychiatry Nov 21.

Lassale C, Batty GD, Steptoe A, Cadar D, Akbaraly TN, Kivimaki M, Zaninotto P (2018). Association of 10-year C-reactive protein trajectories with markers of healthy aging: findings from the English Longitudinal Study of Ageing. The journals of gerontology. Series A, Biological sciences and medical sciences. Feb 15 (in press).

Lepvrier E, Thomas D, Garnier C (2018). Hsp90 quaternary structures and the chaperone cycle: highly flexible dimeric and oligomeric structures and their regulation by co-chaperones. Current Proteomics (in press)

Louvrier J, Duchamp C, Marboutin E, Cubaynes S, Choquet R, Miquel C, Gimenez O (2018). Mapping and explaining wolf recolonization in France using dynamic occupancy models and opportunistic data. Ecography. 41, 647-660.

Mansuy M, Baille S, Canet G, Borie A, Cohen-Solal C, Vignes M, Perrier V, Chevallier N, Le Guern N, Deckert V, Lagrost L, Givalois L , Desrumaux C (2018) Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's Disease. Oncotarget 9(28):19688-19703.

Maurice TStrehaiano M, Duhr F, Chevallier N (2018) Amyloid toxicity is enhanced after pharmacological or genetic invalidation of the σ1 receptor. Behav Brain Res 339:1-10.

Mauriello Jimenez C, Aggad D, Croissant JG, Tresfield K, Laurencin D, Berthomieu D, Cubedo N, Rossel M, Alsaiari S, Khashab NM, Anjum DH, Sougrat R, Roldan-Gutierrez MA, Richeter S, Oliviero E, Raehm L, Charnay C, Cattoën X, Clément S, Wong Chi Man M, Maynadier M, Chaleix V, Sol V, Garcia M, Gary-Bobo M, Bettache N, Durand JO (2018) Porous porphyrin-based organosilica nanoparticles for NIR two-photon photodynamic therapy and gene delivery in Zebrafish. Advanced Functional Materials (in press).

Mestre-Francés N, Serratrice N, Gennetier A, Devau G, Cobo S, Trouche SGFontès PZussy C, De Deurwaerdere P, Salinas S, Mennechet FDJ, Dusonchet J, Schneider BL, Saggio I, Kalatzis V, Luquin-Piudo MR, Verdier JM, Kremer EJ (2018) Exogenous LRRK2G2019Sinduces parkinsonian-like pathology in a nonhuman primate. JCI Insight 3 (14):e98202.

Mestre Frances N, Trouche SG, Fontes P, Lautier C, Devau G, Lasbleiz C, Dhenain M, Verdier JM (2018). Chapter 21: Old gray mouse lemur behavior, cognition and neuropathology. in Conn's Handbook of models for human aging 2ed. Editors Jl Ram and PM Conn.

Mohamet L, Vicky C Jones VC, Dayanithi G, Verkhratsky A (2018). Pathological human astroglia in Alzheimer’s disease: opening new horizons with stem cell technology. Future Neurology 13: 87-100.

Mortamais M, Abdennour M, Bergua V, Tzourio C, Berr C, Gabelle A, Akbaraly TN (2018). Anxiety and 10-Year Risk of Incident Dementia-An Association Shaped by Depressive Symptoms: Results of the Prospective Three-City Study. Frontiers in neuroscience. 12:248.

Moussaed M, Huc-Brandt S, Cubedo N, Silhol M, Murat S, Lebart MC, Kovacs G, Verdier JM, Trousse F, Rossel M, Marcilhac A (2018). Regenerating islet-derived 1α (REG-1α) protein increases tau phosphorylation in cell and animal models of tauopathies. Neurobiology of Disease. 119:136-148.

Noristani HN, They L, Perrin FE (2018). C57BL/6 and Swiss Webster mice display differences in mobility, gliosis, microcavity formation and lesion volume after severe spinal cord injury. Frontiers in Cellular Neurosciences, 12:173.

Noristani HN*, Saint-Martin GP*, Cardoso M, Catteau M, Sidiboulenouar R, Coillot C, Goze-Bac C, Perrin FE (2018). Longitudinal MRI analysis and histological characterization after spinal cord injury in two mouse strains with different functional recovery: gliosis as a key factor. Journal of Neurotrauma, doi: 10.1089/neu.2017.5613.

Poulen G, Perrin FE (2018). Microcebus murinus: a novel promising non-human primate model of spinal cord injury. Editorial Neural Regeneration Research. 13:421-422.

Sabia S, Fayosse A, Dumurgier J, Dugravot A, Akbaraly T, Britton A, Kivimaki M, Singh-Manoux A (2018). Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study. BMJ (Clinical research ed), 362:k2927.

Vermeulen E, Knuppel A, Shipley M, Brouwer IA, Visser M, Akbaraly T, Brunner EJ, Nicolaou M (2018).High-sugar, high-saturated fat dietary patterns do not associate with depressive symptoms in mid-life men and women: prospective study. Journal of Nutrition 148:1598-1604.


Ahue MK, Mamyrbekova-Bekro JA, Maurice T, Pirat JL, Bekro Yl (2017) Preliminary phytochemical screening and protective effect of Erythrina senegalensis in an in vivo mouse model of Alzheimer's disease. J Med Pharmaceut Allied Sci. March:630-644.

Berta T, Perrin FE, Pertin M, Tonello R, Liu YC, Chamessian A, Kato AC, Ji RR, Decosterd I (2017). Gene expression profiling of cutaneous injured and non-injured nociceptord in SNI animal model of neuropathic pain. Scientific Reports, 7:9367. DOI:10.1038/s41598-017-08865-3.

Bonneaud N, Layalle S, Colomb S, Jourdan C, Ghysen A, Severac D, Dantec C, Nègre N, Maschat F (2017) Control of nerve cord formation by Engrailed and Gooseberry-Neuro: a multi-step, coordinated process. Developmental Biology 432:273–285.

Bousquet JB, Bewick M, Cano A, Eklund P, Fico G, Goswami N, Robine JM, et al. (2017) Building bridges for innovation in ageing: synergies between action groups of the EIP on AHA. J Nutr Health Aging 21(1):92-104.

Cambois E, Robine JM (2017) L’allongement de l’espérance de vie en Europe : quelles conséquences pour l’état de santé. Revue européenne des sciences sociales. 55(1):41-67.

Deckert V, Lemaire S, Ripoll PJ, de Barros JP, Labbé J, Borgne CC, Turquois V, Maquart G, Larose D, Desroche N, Ménétrier F, Le Guern N, Lebrun LJ, Desrumaux C, Gautier T, Grober J, Thomas C, Masson D, Houdebine LM, Lagrost L (2017) Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis. Scientific reports 7:3053.

Deere JA, Coulson T, Cubaynes S, Smallegange IM (2017) Unsuccessful dispersal affects life history characteristics of natal populations: The role of dispersal related variation in vital rates. Ecological Modelling, 366, 37-47.

Dubicanac M, Strueve J, Mestre-Francés NVerdier JM, Zimmermann E, Joly M (2017) Photoperiodic regim influences onset of lens opacities in a non-human primate. PeerJ. 5:e3258

Garnier C, Briki F, Nedelec B, Le Pogamp P, Dogan A, Rioux-Leclercq N, Goude R, Beugnet C, Martin L, Delpech M, Bridoux F, Grateau G, Doucet J, Derreumaux P, Valleix S (2017) VLITL is a major cross-β-sheet signal for fibrinogen Aα-chainframeshift variants, Blood 130(25):2799-2807.

Garnier C, Devred F, Byrne D, Puppo R, Roman AY, Malesinski S, Golovin AV, Lebrun R, Ninkina NN, Tsvetkov PO (2017). Zinc binding to RNA recognition motif of TDP-43 induces the formation of amyloid-like aggregates. Scientific reports 7:6812

Goguadze N, Zhuravliova E, Morin D, Mikeladze D, Maurice T (2017) Sigma-1 receptor agonists induce oxidative stress in mitochondria and enhance complex I activity in physiological condition, but protect against pathological oxidative stress. Neurotox Res.  Nov 10; doi: 10.1007/s12640-017-9838-2.

Herr M, Arvieu JJ, Ankri J,. Robine JM (2017) What is the duration of life expectancy in the state of frailty? Estimates in the SIPAF study. European Journal of Ageing. 2017:1-9.

Hiance-Delahaye A, de Schongor FM, Lechowski L, Teillet L, Arvieu JJ, Robine JM, et al. (2017) Potentially inappropriate prescription of antidepressants in old people: characteristics, associated factors, and impact on mortality. Int Psychogeriatr 2017:1-12.

Hirbec HE, Noristani HN, Perrin FE (2017) Microglia responses diversity in acute and chronic neurological diseases: what microglia-specific transcriptomic taught (and did not teach) us. Frontiers in Aging Neuroscience, 9:227.doi: 10.3389/fnagi.2017.00227.

Khalil B, Cabirol-Pol M-J, Miguel L, Whitworth AJ, Lecourtois M, Liévens J-C (2017). Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies. Neurobiology of Aging 54: 71–83

Khalil B, Liévens J-C (2017). Mitochondrial quality control in amyotrophic lateral sclerosis: towards a common pathway? Neural Regeneration Research 12: 1052-1061

Le Corre, Noristani HNMestre-Frances NSaint-Martin G, Coillot C, Goze-bac C, Lonjon NPerrin FE (2017). A novel translational model of spinal cord injury in non-human primate: multi-scale correlations fron behaviour to magnetic resonance imaging. Neurotherapeutics Nov 27. doi: 10.1007/s13311-017-0589-9.

Maurice T, Goguadze N (2017) Role of σ1 Receptors in Learning and Memory and Alzheimer's Disease-Type Dementia. Adv Exp Med Biol 964:213-233.

Maurice T, Goguadze N (2017) Sigma-1 (σ1) Receptor in Memory and Neurodegenerative Diseases. Handb Exp Pharmacol 244:81-108.

MokryJ, Hrebíková H, Chvátalová J, Pisal R, Filip S, Dayanithi G (2017) A cellular muscle scaffolds: Histological and biochemical evaluation. BioMedical Research & Therapy 14S: doi: 10.15419/bmrat.v4iS.300.

Naert G, Ferré V, Keller E, Slender A, Gibbins D, Fisher EMC, Tybulewicz VLJ, Maurice T (2017). In vivo and ex vivo analyses of amyloid toxicity in the Tc1 mouse model of Down syndrome. J Psychopharmacol  doi: 10.1177/0269881117743484.

Noristani HN, Boukhaddaoui H, Saint-Martin GP, Auzer P, Sidiboulenouar R, Lonjon N, Alibert E, Tricaud N, Goze-Bac C, Coillot C, Perrin FE (2017). Microglial alterations after spinal cord injury: a combination of exvivo diffusion MRI and multiphoton study. Frontiers in Aging Neurosciences, 9:230. doi: 10.3389/fnagi.2017.00230.

Noristani HNGerber YN, Sabourin JC, Le Corre M, Lonjon N, Mestre-Frances N, Hirbec H and Perrin FE (2017). RNA-Seq analysis of microglia reveals time-dependent activation of specific genetic programs following spinal cord injury. Frontiers in Molecular Neuroscience, 10:90. doi: 10.3389/fnmol.2017.00090.

Perrier V, Imberdis T, Lafon P-A, Cefis M, Wang Y, Huetter E, Arnaud J-D, Alvarez-Martinez T, Le Guern N, Maquart G, Lagrost L, Desrumaux C (2017) Plasma cholesterol level determines in vivo prion propagation. J. Lipid Res 58:1950-1961.

Robine JM, Jagger C (2017). Health expectancies. In: Jean-Pierre Michel BLB, Finbarr C. Martin, and Jeremy D. Walston, editor. Oxford Textbook of Geriatric Medicine (3 ed): Oxford University Press.

Robine JMCubaynes S (2017). Worldwide demography of centenarians. Mechanisms of Ageing and Development 165:59-67.

Robine JM, Cubaynes S (2017) Espérances de vie, espérances de santé: tendances convergentes ou divergentes sur le plan mondial? in Allongement de la vie: quels défis ? quelles politiques? eds.Guillemard A.-M. et Mascova E.

Robine JM (2017). When climate change encounters the revolution in adult longevity. Aging Clinical and Experimental Research 29(6):1073-4.

Rodríguez Cruz Y, Strehaiano M, Rodríguez Obaya T, García Rodríguez JC, Maurice T (2017) An intranasal formulation of erythropoietin (Neuro-EPO) prevents memory deficits and amyloid toxicity in the APPSwe transgenic mouse model of Alzheimer's disease. J Alz Dis 55(1):231-248.

Salinas S, Constant O, Desmetz C, Barthelemy J, Lemaitre JM, Millhavet O, Nagot N, Perrin FE, Saiz JC, Van de Perre P and Simonin Y (2017). Deleterious effect of Usutu virus on human neural cells. PLOS Neglected Tropical Diseases 11:e0005913

Shivappa N, Hebert JR, Kivimaki M, Akbaraly T (2017). Alternate Healthy Eating Index 2010, Dietary Inflammatory Index and risk of mortality: results from the Whitehall II cohort study and meta-analysis of previous Dietary Inflammatory Index and mortality studies. Br J Nutr Aug;118(3):210-221.

Virtanen M, Ferrie JE, Akbaraly T, Tabak A, Jokela M, Ebmeier KP, Singh-Manoux A, Kivimäki M (2017). Metabolic Syndrome and Symptom Resolution in Depression: A 5-Year Follow-Up of Older Adults. J Clin Psychiatry Jan;78(1):e1-e7.

Yokota RTC, Nusselder WJ, Robine JM, Tafforeau J, Deboosere P, Moura L, et al (2017) Contribution of chronic conditions to functional limitations using a multinomial outcome: results for the older population in Belgium and Brazil. Archives of Public Health 75(68).


Akbaraly TN, Kerleau C, Wyart M, Chevallier N, Ndiaye L, Shivappa N, Hébert J.R, Kivimaki M (2016). Dietary inflammatory index and recurrence of depressive symptoms: results from the Whitehall II study. Clinical Psychological Science, 4(6):1125-34.

Akbaraly TN, Tabak GT, Shipmey, MJ, Mura T, Singh-Manoux A, Ferrie J, Batty GD, Kivimaki M (2016). Little change in diet after onset of type 2 diabetes, metabolic syndrome and obesity in middle-aged adults: 11-year follow-up study. Diabetes Care 39(3):e29-30.

Ballester J, Rodó X, Robine JM, Herrmann FR (2016). European seasonal mortality and influenza incidence due to winter temperature variability. Nature Climate Change (in press)

Charroud C, Le Bars E, Deverdun J, Steffener J, Molino F, Abdennour M, Portet F, Bonafe A, Stern Y, Ritchie K, Akbaraly TN, Menjot de Champfleur N (2016). Memory Performance is related to intrinsic resting state functional connectivity changes in community-dwelling elderly cohort. Neurobiology of learning and memory 132:57-66.

Coillot C, Sidiboulenouar R, Nativel E, Zanca M, Alibert E, Saintmartin G, Noristani HN, Lonjon N, Perrin FE, Goze-Bac C (2016). Signal Modeling of a MRI Ribbon Solenoid Coil Dedicated to Spinal Cord Injuries Investigations. J. of Sensors and Sensor Systems 5, 137–145.

Dayanithi G, Verkhratsky A (2016). Calcium signalling in stem cells: Molecular physiology and multiple roles. Cell Calcium 59: 55-56.

Deverdun J, Akbaraly TN, Charroud C, Abdennour M, Brickman AM, Chemouny S Steffener J, Portet F, Bonafe A,  Stern Y, Ritchie K,  Molino F, Le Bars E, Menjot de Champfleur N (2016). Mean arterial pressure change associated with cerebral blood flow in healthy older adults. Neurobiology of Aging 46: 49-57.

Do-Thi A, Perrin FE, Desclaux M, Saillour P, Amar L, Privat A, Mallet J (2016). Combination of grafted Schwann cells and lentiviral-prevention of glial scar formation improve recovery of spinal cord injured rats. J Chem Neuroanat 76: 48-60.

Dubicanac M, Joly M, Strüve J, Nolte I, Mestre-Francés N, Verdier JM, Zimmermann E (2016). Intraocular pressure in the smallest primate aging model: the gray mouse lemur. Veterinary Ophthalmology doi: 10.1111/vop.12434.

Fernando R, Cotter L, Perrin-Tricaud C, Berthelot J, Bartolami S, Pereira J, Gonzalez S, Suter U, Tricaud N (2016). Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway. Nature Communications 7: 12186.

Forostyak O, Butenko O, Anderova M, Forostyak S, Verkhratsky A, Sykova E, Dayanithi G (2016). Specific profiles of ion channels and ionotropic receptors define adipose- and bone marrow derived stem cells. Stem Cell Research 16: 622-634.

Forostyak O, Forostyak S, Sykova E, Verkhratsky A, Dayanithi G (2016). Physiology of calcium signalling in stem cells of different origins and experimental conditions. Cell Calcium 59: 57-66.

Imberdis T, Ayrolles-Torro A, Duarte, Rodrigues A, Torrent J, Alvarez Martinez MT, Kovacs GGK, Verdier JM, Robitzer M, Perrier V (2016). A fluorescent oligothiophene-Bis-Triazine ligand interacts with PrP fibrils and detects SDS-resistant oligomers in human prion diseases. Molecular Neurodegeneration 11: 11. Highlight Inserm: http://www.inserm.fr/index.php/actualites/rubriques/actualites-recherche/maladies-a-prions-un-meilleur-test-diagnostic-a-l-etude 

Imberdis T, Robitzer M, Perrier V (2016). Trapping the oligomers: new promises in neurosciences. Oncotarget doi: 10.18632/oncotarget. 13800.

Kortus S, SrinivasanC, Forostyak O, Ueta Y, Sykova E, Chvatal A, Zapotosky M, Verkhratsky A, Dayanithi G (2016). Physiology of spontaneous [Ca2+]ioscillations in the isolated vasopressin and oxytocin neurones of the rat supraoptic nucleus. Cell Calcium 59: 280-288.

Kortus S, SrinivasanC, Forostyak O, Zapotosky M, Ueta Y, Chvatal A, Sykova E, Verkhratsky A, Dayanithi G (2016). Sodium-calcium exchanger and R-type Ca2+channels mediate spontaneous [Ca2+]ioscillations in magnocellular neurones of the rat supraoptic nucleus. Cell Calcium 59: 289-298.

Labour MN, Vigier S, Lerner D, Marcilhac A, Belamie E (2016). 3D compartmented model to study the neurite-related toxicity of Aβ aggregates included in collagen gels of adaptable porosity. Acta Biomaterialia 37:38-49.

Marelli C., Maschat F (2016). P42: a novel and promising peptide-based therapy for Huntington’s disease. Orphanet Journal of Rare Diseases. 11:24. DOI: 10.1186/s13023-016-0405-3.

Maurice T (2016). Protection by sigma-1 receptor agonists is synergic with donepezil, but not with memantine, in a mouse model of amyloid-induced memory impairments. Behavioural Brain Research 296: 270-278.

Maurice T, Strehaiano M, Siméon N, Bertrand C, Chatonnet A (2016) Learning performances and vulnerability to amyloid toxicity in the butyrylcholinesterase knockout mouse. Behavioural Brain Research 296: 351-60.

Maurice T, Goguadze N (2016). Role of σ1 receptors in leaning and memory and Alzheimer's disease-type dementia. In: Sigma Receptors: Their Role in Disease and as Therapeutic Targets (Smith SB, Su TP, Eds), Springer’s Advances in Experimental Medicine and Biology series, New York.

Maurice T, Goguadze N (2016). Sigma-1 (σ1) receptors in memory and neurodegenerative diseases. In: Sigma Proteins: Molecular Pharmacology in Physiology and Pathophysiology (Kim FJ, Pasternak GW, Eds), Springer’s Handbook of Experimental Pharmacology series, New York.

Nasri A, Valverde A, Roche DB, Desrumaux C, Clair P, Beyrem H, Chaloin L, Ghysen A, Perrier V (2016). Neurotoxicity of a biopesticide analog on zebrafish larvae at nanomolar concentrations. International Journal of Molecular Sciences 17: 2137.

Noristani HNPerrin FE (2016). Astrocyte-to-neuron conversion induced by spinal cord injury. Oncotarget 7: 83831-83832.

Noristani HN, Sabourin JCC, Boukhaddaoui H, Chan-Seng E, Gerber YN, Perrin FE (2016). Spinal cord injury induces astroglial conversion towards neuronal lineage. Molecular Neurodegeneration 11: 68.

Pineau F, Canet G, Desrumaux C, Hunt H, Chevallier N, Ollivier M, Belanoff JK, Givalois L (2016). New selective glucocorticoid receptor modulators reverse amyloid-ß peptide-induced hippocampus toxicity. Neurobiology of Aging 45:109-122.

Reggiani AM, Simoni E, Caporaso R, Meunier J, Keller E, Maurice T, Minarini A, Rosini M, Cavalli A (2016). In Vivo Characterization of ARN14140, a Memantine/Galantamine-Based Multi-Target Compound for Alzheimer’s Disease. Scientific Reports 6: 33172.

Robine JM (2016) Données démographiques et épidémiologiques. In: Aquino JP, Cudennec T, Barthélémy L, editors. Guide pratique du vieillissement. Issy les Moulineaux: Elsevier Masson.

Robine JM (2016) Centenaires et supercentenaires. In: Trivalle C, editor. Gérontologie Préventive - Eléments de prévention du vieillissement pathologique. 3ème Edition ed. Issy les Moulineaux: Elsevier Masson.

Robine JM (2016) La révolution de la longévité des adultes. Gerontologie et Société. 39:21-40.

Rodríguez Cruz Y, Strehaiano M, Rodríguez Obaya T, García Rodríguez JC, Maurice T (2016). An intranasal formulation of erythropoietin (Neuro-EPO) prevents memory deficits and amyloid toxicity in the APPSwe transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease 55: 231-48.

Saunders PA, Franco T, Sottas C, Maurice T, Ganem G, Veyrunes F (2016). Masculinised Behaviour of XY Females in a Mammal with Naturally Occuring Sex Reversal. Scientif Reports 6: 22881.

Schirmer C, Lepvrier E, Duchesne L, Decaux O, Thomas D, Delamarche C, Garnier C (2016). Hsp90 directly interacs, in vitro, with amyloid structures and modulates their assembly and disassembly Biochimical Biophysical Acta General Subjects 1860: 2598-2609

SkoloudikL, Chrobok V, Kalfert D, Koci Z, Sykova E, Chumak T, Popelar J, Syka J, Laco J, Dedková J, Dayanithi G, Filip S (2016). Human multipotent mesenchymal stromal cells in the treatment of postoperative temporal bone defect: an animal model. Cell Transplantation 25: 1405-1414.

Verdier JM, Mestre-Francés N (2016) Microcebus murinus- a unique primate for modeling human brain disorders, including Alzheimer’s disease and bovine spongiform encephalopathy. In: The Dwarf and Mouse Lemurs of Madagascar: Biology, Behavior and Conservation Biogeography of the Cheirogaleidae, Eds. SM Lehmann, U Radespiel & E Zimmermann, Cambridge University Press, Cambridge (UK), vol 73, pp161-173.

Vestergaard S, Andersen-Ranberg K, Skytthe A, Christensen K, Robine JM, Jeune B (2016) Health and function assessments in two adjacent Danish birth cohorts of centenarians: Impact of design and methodology. European Journal of Ageing 13:15-23.

Yokota RT, Van der Heyden J, Nusselder WJ, Robine JM, Tafforeau J, Deboosere P, et al. (2016) Impact of Chronic Conditions and Multimorbidity on the Disability Burden in the Older Population in Belgium. The journals of gerontology Series A, Biological sciences and medical sciences 71:903-9.

Yokota RT, Nusselder WJ, Robine JM, Tafforeau J, Deboosere P, Van Oyen H (2016) Contribution of Chronic Conditions to the Disability Burden across Smoking Categories in Middle-Aged Adults, Belgium. PloS One 11(4):e0153726.

Zimmermann E, Radespiel U, Mestre-Francés N, Verdier JM (2016) Life history variation in mouse lemurs (Microcebus murinus, M. lehilahytsara): the effect of environmental and phylogenetic determinants. In: The Dwarf and Mouse Lemurs of Madagascar: Biology, Behavior and Conservation Biogeography of the Cheirogaleidae, Eds. SM Lehmann, U Radespiel & E Zimmermann, Cambridge University Press, Cambridge (UK), vol 73, pp174-194.


Akbaraly TN, Jaussent I, Besset A, Bertrand M, Barberger-Gateau P, Ritchie K, Ferrie JE, Kivimaki M, Dauvilliers Y (2015) Sleep complaints and metabolic syndrome in an elderly population: the Three-City Study. Am J Geriatr Psychiatry 23:818-828.

Akbaraly TN, Shipley MJ, Ferrie JE, Virtanen M, Lowe G, Hamer M, Kivimaki M (2015) Long-term adherence to healthy dietary guidelines and chronic inflammation in the prospective Whitehall II study. Am J Med 128:152-160 e154.

Angebault C, Guichet PO, Talmat-Amar Y, Charif M, Gerber S, Fares-Taie L, Gueguen N, Halloy F, Moore D, Amati-Bonneau P, Manes G, Hebrard M, Bocquet B, Quiles M, Piro-Mégy C, Teigell M, Delettre C, Rossel M,  et al. (2015) Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies. Am J Hum Genet. 97(5):754-60 Audemars Piguet Replica

Berger N, Van Oyen H, Cambois E, Fouweather T, Jagger C, Nusselder W, Robine JM (2015) Assessing the validity of the Global Activity Limitation Indicator in fourteen European countries. BMC Med Res Methodol 15:1.

Besson M-T, Alegría K, Garrido-Gerter P, Barros LF, Liévens J-C (2015). Enhanced neuronal glucose transporter expression reveals metabolic choice in a HD Drosophila model. PloS One 10: e0118765

Blain H, Léglise MS, Bernard PL, Dupeyron A, Pastor E, Strubel D, Akbaraly T, Abecassis F, Adnet PA, Alomène B, Amouyal M, Bardy B, Battesti MP, Baptista G, Boubakri C, Burille J, Calmels MV, Canovas G, Combe B, Delignières D, Dupeyron G, Engberink O, Gressard F, Heve D, Jakovenko D, Jeandel C, Lapierre M, Laffont I, Laurent C, Lognos B, Lussert JM, Mandrick K, Marmelat V, Martin-Gousset P, Matheron A, Mercier G, Meunier C, Morel J, Ninot G, Nouvel F, Pasdelou MP, Pélissier JY, Perrey S, Picot MC, Pinto N, Raffort N, Ramdani S, Radier-Pontal F, Royère E, Rédini-Martinez I, Robine JM, Roux E, Savy JL, Stephan Y, Tallon G, Torre K, Verdier JM, Vergotte G, Viollet E, Bedbrook A, Granier S, Camuzat T, Bourret R, Jonquet O, de la Coussaye JE, Noguès M, Aoustin M, Domy P, Bringer J, Mercier J, Bousquet J (2015). Living Lab MACVIA-LR. Equilibrium and the prevention of falls. Presse Med 44 Suppl 1: S23-30.

Bourret R, Mercier G, Mercier J, Jonquet O, De La Coussaye JE, Bousquet PJ, Robine JM, Bousquet J (2015) Comparison of two methods to report potentially avoidable hospitalizations in France in 2012: a cross-sectional study. BMC Health Serv Res 15:4.

Bousquet J, Anto JM, Berkouk K, Gergen P, Antunes JP, Auge P, Camuzat T, Bringer J, Mercier J, Best N, Bourret R, Akdis M, Arshad SH, Bedbrook A, Berr C, Bush A, Cavalli G, Charles MA, Clavel-Chapelon F, Gillman M, Gold DR, Goldberg M, Holloway JW, Iozzo P, Jacquemin S, Jeandel C, Kauffmann F, Keil T, Koppelman GH, Krauss-Etschmann S, Kuh D, Lehmann S, Carlsen KC, Maier D, Mechali M, Melen E, Moatti JP, Momas I, Nerin P, Postma DS, Ritchie K, Robine JM, Samolinski B, Siroux V, Slagboom PE, Smit HA, Sunyer J, Valenta R, Van de Perre P, Verdier JM, Vrijheid M, Wickman M, Yiallouros P, Zins M (2015) Developmental determinants in non-communicable chronic diseases and ageing. Thorax 70:595-597.

Charroud C, Steffener J, Bars EL, Deverdun J, Bonafe A, Abdennour M, Portet F, Molino F, Stern Y, Ritchie K, Champfleur NM, Akbaraly TN (2015) Working memory activation of neural networks in the elderly as a function of information processing phase and task complexity. Neurobiol Learn Mem 125: 2137-44.

Cheung SL, Yip SF, Branch LG, Robine JM (2015) Decreased Proportion of Dementia-Free Life Expectancy in Hong Kong SAR. Dement Geriatr Cogn Disord 40:72-84.

Chumakov I, Nabirotchkin S, Cholet N, Milet A, Boucard A, Toulorge D, Pereira Y, Graudens E, Traore S, Foucquier J, Guedj M, Vial E, Callizot N, Steinschneider R, Maurice T, Bertrand V, Scart-Gres C, Hajj R, Cohen D (2015) Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy. Sci Rep 5:7608.

Detrait E, Maurice T, Hanon E, Leclercq K, Lamberty Y (2015) Lack of synaptic vesicle protein SV2B protects against amyloid-beta(2)(5)(-)(3)(5)-induced oxidative stress, cholinergic deficit and cognitive impairment in mice. Behav Brain Res 271:277-285.

Ferrie JE, Kivimaki M, Akbaraly TN, Tabak A, Abell J, Davey Smith G, Virtanen M, Kumari M, Shipley MJ (2015) Change in Sleep Duration and Type 2 Diabetes: The Whitehall II Study. Diabetes Care 38:1467-1472.

Fouweather T, Gillies C, Wohland P, Van Oyen H, Nusselder W, Robine JM, Cambois E, Jagger C (2015) Comparison of socio-economic indicators explaining inequalities in Healthy Life Years at age 50 in Europe: 2005 and 2010. Eur J Public Health.

Herr M, Robine JM, Aegerter P, Arvieu JJ, Ankri J (2015) Contribution of socioeconomic position over life to frailty differences in old age: comparison of life-course models in a French sample of 2350 old people. Ann Epidemiol 25:674-680 e671.

Herr M, Robine JM, Pinot J, Arvieu JJ, Ankri J (2015) Polypharmacy and frailty: prevalence, relationship, and impact on mortality in a French sample of 2350 old people. Pharmacoepidemiol Drug Saf 24:637-646.

Ikehara S, Tabak AG, Akbaraly TN, Hulman A, Kivimaki M, Forouhi NG, Iso H, Brunner EJ (2015). Age trajectories of glycaemic traits in non-diabetic South Asian and white individuals: the Whitehall II cohort study. Diabetologia 58: 534-42.

Joseph-Mathurin N, Dorieux O, Trouche SG, Boutajangout A, Kraska A, Fontes PVerdier JM, Sigurdsson EM, Mestre-Frances N, Dhenain M (2015) Amyloid beta immunization worsens iron deposits in the choroid plexus and cerebral microbleeds. Neurobiol Aging 34:2613-2622.

Khalil B, El Fissi N, Aouane A, Cabirol-Pol M-J, Rival T, Liévens J-C (2015). PINK1-induced mitophagy promotes neuroprotection in Huntington’s disease. Cell Death and Disease 6: e1617 Replica Breitling

Lowe R, Ballester J, Creswick J, Robine JM, Herrmann FR, Rodo X (2015) Evaluating the performance of a climate-driven mortality model during heat waves and cold spells in Europe. Int J Environ Res Public Health 12:1279-1294.

Malik M, Rangel-Barajas C, Sumien N, Su C, Singh M, Chen Z, Huang RQ, Meunier J, Maurice T, Mach RH, Luedtke RR (2015) The Effects of Sigma-1 Receptor Selective Ligands on Muscarinic Receptor Antagonist Induced Cognitive Deficits in Mice. Br J Pharmacol (in press).

Maurice T (2015) Protection by sigma-1 receptor agonists is synergic with donepezil, but not with memantine, in a mouse model of amyloid-induced memory impairments. Behav Brain Res 296:270-278.

Maurice T, Strehaiano M, Simeon N, Bertrand C, Chatonnet A (2015) Learning performances and vulnerability to amyloid toxicity in the butyrylcholinesterase knockout mouse. Behav Brain Res (in press).

Meunier J, Borjini N, Gillis C, Villard V, Maurice T (2015) Brain toxicity and inflammation induced in vivo in mice by the amyloid-beta forty-two inducer aftin-4, a roscovitine derivative. J Alzheimers Dis 44:507-524.

Moriya T, Shibasaki R, Kayano T, Takebuchi N, Ichimura M, Kitamura N, Asano A, Hosaka YZ, Forostyak O, Verkhratsky A, Dayanithi G, Shibuya I (2015) Full-length transient receptor potential vanilloid 1 channels mediate calcium signals and possibly contribute to osmoreception in vasopressin neurones in the rat supraoptic nucleus. Cell Calcium 57:25-37.

Naert GZussy C, Tran-Van-Ba C, Chevallier N, Tang YP, Maurice TGivalois L (2015) Involvement of endogenous brain-derived neurotrophic factor in hypothalamic-pituitary-adrenal axis activity. J Neuroendocrinol 27, 850-860.

Naert GFerre V, Meunier J, Keller E, Malmstrom S, Givalois L, Carreaux F, Bazureau JP, Maurice T (2015) Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Abeta peptide administration in mice. Eur Neuropsychopharmacol 25, 2170-2182.

Omi T, Tanimukai H, Kanayama D, Sakagami Y, Tagami S, Okochi M, Morihara T, Sato M, Yanagida K, Kitasyoji A, Hara H, Imaizumi K, Maurice TChevallier N, Marchal S, Takeda M, Kudo T (2015) Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor. Cell Death Dis 5:e1332.

Opie RS, Itsiopoulos C, Parletta N, Sanchez-Villegas A, Akbaraly TN, Ruusunen A, Jacka FN (2015) Dietary recommendations for the prevention of depression. Nutr Neurosci (in press).

Pinot J, Herr M, Robine JM, Aegerter P, Arvieu JJ, Ankri J (2015) Does the Prescription of Anxiolytic and Hypnotic Drugs Increase Mortality in Older Adults? J Am Geriatr Soc 63:1263-1265.

Sarris J, Logan AC, Akbaraly TN, Amminger GP, Balanza-Martinez V, Freeman MP, Hibbeln J, Matsuoka Y, Mischoulon D, Mizoue T, Nanri A, Nishi D, Ramsey D, Rucklidge JJ, Sanchez-Villegas A, Scholey A, Su KP, Jacka FN (2015) Nutritional medicine as mainstream in psychiatry. Lancet Psychiatry 2:271-274. linkreplicawatches.com

Sarris J, Logan AC, Akbaraly TN, Paul Amminger G, Balanza-Martinez V, Freeman MP, Hibbeln J, Matsuoka Y, Mischoulon D, Mizoue T, Nanri A, Nishi D, Parletta N, Ramsey D, Rucklidge JJ, Sanchez-Villegas A, Scholey A, Su KP, Jacka FN (2015) International Society for Nutritional Psychiatry Research consensus position statement: nutritional medicine in modern psychiatry. World Psychiatry 14:370-371.

Trousse F, Poluch S, Pierani A, Dutriaux A, Bock HH, Nagasawa T, Verdier JMRossel M (2015) CXCR7 Receptor Controls the Maintenance of Subpial Positioning of Cajal-Retzius Cells. Cereb Cortex 25:3446-3457.

Verdier JMAcquatella ILautier CDevau GTrouche SLasbleiz CMestre-Frances N (2015) Lessons from the analysis of nonhuman primates for understanding human aging and neurodegenerative diseases. Front Neurosci 9:64.

Virtanen M, Shipley MJ, Batty GD, Hamer M, Allan CL, Lowe GD, Ebmeier KP, Akbaraly TN, Alenius H, Haapakoski R, Singh-Manoux A, Kivimaki M (2015). Interleukin-6 as a predictor of symptom resolution in psychological distress: a cohort study. Psychological medicine 45(10): 2137-44.

Yokota RT, Berger N, Nusselder WJ, Robine JM, Tafforeau J, Deboosere P, Van Oyen H (2015) Contribution of chronic diseases to the disability burden in a population 15 years and older, Belgium, 1997-2008. BMC Public Health 15:229.


Arribat Y, Talmat-Amar Y, Paucard A, Lesport P, Bonneaud N, Bauer C, Bec N, Parmentier ML, Benigno L, Larroque C, Maurel P, Maschat F (2014) Systemic delivery of P42 peptide: a new weapon to fight Huntington's disease. Acta Neuropathol Commun 2:86.

Clavier A, Baillet A, Rincheval-Arnold A, Coleno-Costes A, Lasbleiz C, Mignotte B, Guenal I (2014) The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA. Cell Death Dis 5:e1405

Detrait E, Maurice T, Hanon E, Leclercq K, Lamberty Y (2014) Lack of synaptic vesicle protein SV2B protects against amyloid-beta(2)(5)(-)(3)(5)-induced oxidative stress, cholinergic deficit and cognitive impairment in mice. Behav Brain Res 271:277-285.

Dutta A, Henley W, Robine JM, Llewellyn D, Langa KM, Wallace RB, Melzer D (2014) Aging children of long-lived parents experience slower cognitive decline. Alzheimers Dement 10:S315-322.

El Bitar F, Meunier J, Villard V, Almeras M, Krishnan K, Covey DF, Maurice T, Akwa Y (2014) Neuroprotection by the synthetic neurosteroid enantiomers ent-PREGS and ent-DHEAS against Abeta(2)(5)(-)(3)(5) peptide-induced toxicity in vitro and in vivo in mice. Psychopharmacology (Berl) 231:3293-3312.

Filip S, Mokry J, Vavrova J, Sinkorova Z, Micuda S, Sponer P, Filipova A, Hrebikova H, Dayanithi G (2014) The peripheral chimerism of bone marrow-derived stem cells after transplantation: regeneration of gastrointestinal tissues in lethally irradiated mice. J Cell Mol Med 18:832-843.

Givalois L The glucocorticoid receptors regulation in Alzheimer's disease (2014) Neurobiol Aging 35:e17-18.

Graciarena M, Dambly-Chaudiere C, Ghysen A (2014) Dynamics of axonal regeneration in adult and aging zebrafish reveal the promoting effect of a first lesion. Proc Natl Acad Sci U S A 111:1610-1615.

Herr M, Arvieu JJ, Aegerter P, Robine JM, Ankri J (2014) Unmet health care needs of older people: prevalence and predictors in a French cross-sectional survey. Eur J Public Health 24:808-813.

Huc-Brandt S, Hieu N, Imberdis T, Cubedo N, Silhol M, Leighton PL, Domaschke T, Allison WT, Perrier V, Rossel M (2014) Zebrafish prion protein PrP2 controls collective migration process during lateral line sensory system development. PLoS One 9:e113331.

Imberdis T, Ayrolles-Torro A, Verdier JM, Perrier V (2014) Thienyl pyrimidine derivatives with PrP(Sc) oligomer-inducing activity are a promising tool to study prions. Curr Top Med Chem 13:2477-2483.

Lahmy V, Long R, Morin D, Villard V, Maurice T (2014) Mitochondrial protection by the mixed muscarinic/sigma1 ligand ANAVEX2-73, a tetrahydrofuran derivative, in Abeta25-35 peptide-injected mice, a nontransgenic Alzheimer's disease model. Front Cell Neurosci 8:463.

Omi T, Tanimukai H, Kanayama D, Sakagami Y, Tagami S, Okochi M, Morihara T, Sato M, Yanagida K, Kitasyoji A, Hara H, Imaizumi K, Maurice T, Chevallier N, Marchal S, Takeda M, Kudo T (2014) Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor. Cell Death Dis 5:e1332

Serratrice N, Cubizolle A, Ibanes S, Mestre-Frances N, Bayo-Puxan N, Creyssels S, Gennetier A, Bernex F, Verdier JM, Haskins ME, Couderc G, Malecaze F, Kalatzis V, Kremer EJ (2014) Corrective GUSB transfer to the canine mucopolysaccharidosis VII cornea using a helper-dependent canine adenovirus vector. J Control Release 181:22-31.

Viero C, Forostyak O, Sykova E, Dayanithi G (2014) Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS. Front Cell Dev Biol 2:36.


Acquatella-Tran Van Ba IImberdis TPerrier V (2013) From prion diseases to prion-like propagation mechanisms of neurodegenerative diseases. Int J Cell Biol 2013:975832.

Bertrand A, Pasquier A, Petiet A, Wiggins C, Kraska A, Joseph-Mathurin N, Aujard F, Mestre-Frances N, Dhenain M (2013) Micro-MRI study of cerebral aging: ex vivo detection of hippocampal subfield reorganization, microhemorrhages and amyloid plaques in mouse lemur primates. PLoS One 8:e56593

Brureau AZussy CDelair BOgier CIxart GMaurice TGivalois L (2013) Deregulation of hypothalamic-pituitary-adrenal axis functions in an Alzheimer's disease rat model. Neurobiol Aging. 34(5):1426-39. Highlight in "Science & Santé" N°14, mai-juin 2013.

Cocks G, Romanyuk N, Amemori T, Jendelova P, Forostyak O, Jeffries AR, Perfect L, Thuret S, Dayanithi G, Sykova E, Price J (2013) Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneurons. Stem Cell Res Ther 4:69.

Deckert V, Kretz B, Habbout A, Raghay K, Labbe J, Abello N, Desrumaux C, Gautier T, Lemaire-Ewing S, Maquart G, Le Guern N, Masson D, Steinmetz E, Lagrost L (2013) Development of abdominal aortic aneurysm is decreased in mice with plasma phospholipid transfer protein deficiency. Am J Pathol 183:975-986.

Desrumaux C, Pisoni A, Meunier J, Deckert V, Athias A, Perrier V, Villard V, Lagrost L, Verdier JMMaurice T (2013) Increased amyloid-beta peptide-induced memory deficits in phospholipid transfer protein (PLTP) gene knockout mice. Neuropsychopharmacology 38:817-825.

Forostyak O, Romanyuk N, Verkhratsky A, Sykova E, Dayanithi G (2013) Plasticity of calcium signaling cascades in human embryonic stem cell-derived neural precursors. Stem Cells Dev 22:1506-1521.

Herr M, Arvieu JJ, Aegerter P, Robine JM, Ankri J (2013) Unmet health care needs of older people: prevalence and predictors in a French cross-sectional survey. Eur J Public Health 24:808-813.

Joseph-Mathurin N, Dorieux O, Trouche SG, Boutajangout A, Kraska A, Fontes PVerdier JM, Sigurdsson EM, Mestre-Frances N, Dhenain M (2013) Amyloid beta immunization worsens iron deposits in the choroid plexus and cerebral microbleeds. Neurobiol Aging 34:2613-2622.

Lahmy V, Meunier J, Malmstrom S, Naert GGivalois L, Kim SH, Villard V, Vamvakides A, Maurice T (2013) Blockade of Tau hyperphosphorylation and Abeta(1-42) generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and sigma1 receptor agonist, in a nontransgenic mouse model of Alzheimer's disease. Neuropsychopharmacology 38:1706-1723.

Martin S, Zekri L, Metz A, Maurice T, Chebli K, Vignes M, Tazi J (2013) Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons. J Neurochem 125: 175-184.

Maurice T, Mustafa MH, Desrumaux C, Keller E, Naert G, de la C. Garcia-Barcelo M., Rodriguez Cruz Y, Garcia Rodriguez JC (2013) Intranasal formulation of erythropoietin (EPO) showed potent protective activity against amyloid toxicity in the Abeta(25-35) non-transgenic mouse model of Alzheimer's disease. J Psychopharmacol 27:1044-1057.

Meunier J, Villard V, Givalois LMaurice T (2013) The gamma-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl] (2,5-difluorophenyl) amino]ethyl-5-fluorobenzen butanoic acid (BMS-299897) alleviates Abeta(1-42) seeding and short-term memory deficits in the Abeta(25-35) mouse model of Alzheimer's disease. Eur J Pharmacol 698:193-199.

Noh MY, Koh SH, Kim SM, Maurice T, Ku SK, Kim SH (2013) Neuroprotective effects of donepezil against Abeta42-induced neuronal toxicity are mediated through not only enhancing PP2A activity but also regulating GSK-3beta and nAChRs activity. J Neurochem 127:562-574.

Robine JM, Cambois E, Nusselder W, Jeune B, Oyen HV, Jagger C (2013) The joint action on healthy life years (JA: EHLEIS). Arch Public Health 71:2.

Schuster K, Ghysen A (2013) Labeling second-order sensory neurons in the posterior lateral-line system of zebrafish. Cold Spring Harb Protoc 2013:1175-1177.

Schuster K, Ghysen A (2013) Labeling hair cells and afferent neurons in the posterior lateral-line system of zebrafish. Cold Spring Harb Protoc 2013:1172-1174.

Schuster K, Ghysen A (2013) Making mosaic fish primordia by focal electroporation. Cold Spring Harb Protoc 2013:1169-1171.

Schuster K, Ghysen A (2013) Labeling defined cells or subsets of cells in zebrafish by Kaede photoconversion. Cold Spring Harb Protoc 2013.

Schuster K, Ghysen A (2013) Time-lapse analysis of primordium migration during the development of the fish lateral line. Cold Spring Harb Protoc 2013.

Zussy CBrureau AKeller EMarchal SBlayo CDelair BIxart GMaurice TGivalois L (2013) Alzheimer's Disease Related Markers, Cellular Toxicity and Behavioral Deficits Induced Six Weeks after Oligomeric Amyloid-beta Peptide Injection in Rats. PLoS One 8:e53117.

Wada H, Dambly-Chaudière C, Kawakami K, Ghysen A (2013) Innervation is required for sense organ development in the lateral line system of adult zebrafish. Proc Natl Acad Sci U S A. 110:5659-64.

Wada H, Ghysen A, Asakawa K, Abe G, Ishitani T, Kawakami K (2013) Wnt/Dkk negative feedback regulates sensory organ size in zebrafish. Curr Biol 23:1559-1565.


Acquatella-Tran Van Ba I, Marchal S, Francois F, Silhol M, Lleres C, Michel B, Benyamin Y, Verdier JM, Trousse F, Marcilhac A (2012) Regenerating islet-der ived 1alpha (Reg-1alpha) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor. J Biol Chem 287:4726-4739.

Alba R, Bradshaw AC, Mestre-Frances N, Verdier JM, Henaff D, Baker AH (2012) Coagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus). Gene Ther 19:109-113.

Berka K, Hendrychová T, Anzenbacherová E, Lange R, Mašek V, Anzenbacher P, Otyepka M ( 2012) Binding of Quinidine Radically Increases the Stability and Decreases the Flexibility of Cytochrome P450 2D6 Active Site. J. Inorg. Biochem. 110: 46-50.

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Duclot F, Lapierre M, Fritsch S, White R, Parker MG, Maurice T, Cavailles V (2012) Cognitive impairments in adult mice with constitutive inactivation of RIP140 gene expression. Genes Brain Behav 11:69-78.

Espallergues J, Mamiya T, Vallee M, Koseki T, Nabeshima T, Temsamani J, Laruelle C, Maurice T (2012) The antidepressant-like effects of the 3beta-hydroxysteroid dehydrogenase inhibitor trilostane in mice is related to changes in neuroactive steroid and monoamine levels. Neuropharmacology 62:492-502.

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Labour MN, Banc A, Tourrette A, Cunin F, Verdier JM, Devoisselle JM, Marcilhac A, Belamie E (2012) Thick collagen-based 3D matrices including growth factors to induce neurite outgrowth. Acta Biomater 8:3302-3312.

Languille S, Blanc S, Blin O, Canale CI, Dal-Pan A, Devau G, Dhenain M, Dorieux O, Epelbaum J, Gomez D, Hardy I, Henry PY, Irving EA, Marchal J, Mestre-Frances N, Perret M, Picq JL, Pifferi F, Rahman A, Schenker E, Terrien J, Thery M, Verdier JM, Aujard F (2012) The grey mouse lemur: a non-human primate model for ageing studies. Ageing Res Rev 11:150-162.

Lemos JR, Ortiz-Miranda SI, Cuadra, AE Velazquez-Marrero C, Custer EE, Dad T, Dayanithi G. (2012) Modulation/physiology of calcium channel sub-types in neurosecretory terminals. Cell Calcium 51 (3-4):284-292

Marchal S, Marabotti A, Staiano M, Varriale A, Domaschke T, Lange R, D'Auria S (2012) Under pressure that splits a family in two. The case of lipocalin family. PLoS One 7:e50489.

Marchal S, Givalois L, Verdier JM, Mestre-Frances N (2012) Distribution of lithostathine in the mouse lemur brain with aging and Alzheimer's-like pathology. Neurobiol Aging 33:431 e415-425.

Menardo J, Tang Y, Ladrech S, Lenoir M, Casas F, Michel C, Bourien J, Ruel J, Rebillard G, Maurice T, Puel JL, Wang J (2012) Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea. Antioxid Redox Signal 16:263-274.

Mestre-Frances N, Nicot S, Rouland S, Biacabe AG, Quadrio I, Perret-Liaudet A, Baron T, Verdier JM (2012) Oral transmission of L-type bovine spongiform encephalopathy in primate model. Emerg Infect Dis 18:142-145.

Moriya T, Kayano T, Kitamura N, Hosaka YZ, Asano A, Forostyak O, Verkhratsky A, Viero C, Dayanithi G, Toescu EC, Shibuya I. (2012) Vasopressin-induced intracellular Ca2+ concentration responses in non-neuronal cells of the rat dorsal root ganglion. Brain Research 1483: 1-12.

Nicot S, Bencsik A, Morignat E, Mestre-Frances N, Perret-Liaudet A, Baron T (2012) Differentiation of prions from L-type BSE versus sporadic Creutzfeldt-Jakob disease. Emerg Infect Dis 18:2028-2031.

Phillips RS, Wang AK, Marchal S, Lange R (2012) Effects of Pressure and Osmolytes on the Allosteric Equilibria of Salmonella typhimurium Tryptophan Synthase. Biochemistry 51:9354-9363.

Robine JM, Michel JP, Herrmann FR (2012) Excess male mortality and age-specific mortality trajectories under different mortality conditions: a lesson from the heat wave of summer 2003. Mech Ageing Dev 133:378-386.

Toescu EC, Dayanithi G (2012) Neuroendocrine signaling: Natural variations on a Ca2+ theme. Cell Calcium 51 (3-4):207-211.

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Chevallier N, Keller E, Maurice T (2011) Behavioural phenotyping of knockout mice for the sigma-1 (sigma) chaperone protein revealed gender-related anxiety, depressive-like and memory alterations. J Psychopharmacol 25:960-975.

El Moustaine D, Perrier V, Acquatella-Tran Van Ba I, Meersman F, Ostapchenko VG, Baskakov IV, Lange R, Torrent J (2011) Amyloid features and neuronal toxicity of mature prion fibrils are highly sensitive to high pressure. J Biol Chem 286:13448-13459.

Espallergues J, Temsamani J, Laruelle C, Urani A, Maurice T (2011) The antidepressant-like effect of the 3beta-hydroxysteroid dehydrogenase inhibitor trilostane involves a regulation of beta-type estrogen receptors. Psychopharmacology (Berl) 214:455-463.

Hendrychova T, Anzenbacherova E, Hudecek J, Skopalik J, Lange R, Hildebrandt P, Otyepka M, Anzenbacher P (2011) Flexibility of human cytochrome P450 enzymes: molecular dynamics and spectroscopy reveal important function-related variations. Biochim Biophys Acta 1814:58-68.

Kraska A, Dorieux O, Picq JL, Petit F, Bourrin E, Chenu E, Volk A, Perret M, Hantraye P, Mestre-Frances N, Aujard F, Dhenain M (2011) Age-associated cerebral atrophy in mouse lemur Primates. Neurobiol Aging 32(5):894-906.

Naert G, Ixart G, Maurice T, Tapia-Arancibia L, Givalois L (2011) Brain-derived neurotrophic factor and hypothalamic-pituitary-adrenal axis adaptation processes in a depressive-like state induced by chronic restraint stress. Mol Cell Neurosci 46:55-66.

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