Professors

Bartolami Sylvain

bartolami

PhD, Associate Professor, University of Montpellier

Contact: sylvain.bartolami(at)univ-montp2.fr / sylvain.bartolami(at)umontpellier.fr

Team 5: Integrative Biology of Neuroregenaration

Website: http://schwann.free.fr

Resume

Presentation 

After a bachelor in animal physiology (University Grenoble I), I moved to Brighton and took part in a research project studying the development of the chick inner ear (University of Sussex, Prof. Richardson’s Lab). Then, I undertook a master degree in Biochemistry Molecular and Cellular Biology (University Montpellier 2) followed by a PhD degree (Prof. Pujol’s Lab, University Montpellier 2). The subject of my thesis was the characterisation of the muscarinic innervation in the cochlea. My postdoc was carried out at the University of Michigan (Prof. Schacht’s Lab) where I studied the motile behaviour of the auditory cells. Back to France , I jointed a team involved in the neurobiology of balance disorders (Prof Sans and Dr Chabbert, University Montpellier 2 and Montpellier Institute of Neurosciences) and started, amongst others, researches on the physiology of transitional cells of the vestibular neuroepithelium and on the proliferative properties of the vestibular Schwann cells. In the past years, I kept on working in the glial cell field and got involved in the study of the molecular mechanisms underlying the myelinisation of peripheral nerves by Schwann cells (Dr Tricaud’s team, Montpellier Institute of Neurosciences). At present, the Profs Perrin and Verdier (University of Montpellier, MMDN Lab) proved me with the opportunity to start a new challenge: understanding the glial cell responses following spinal cord injury. Our goal is to determine conditions that will favour neuroregeneration in lesioned spinal cord. (List of publications is given in the curriculum vitae file)

Chevallier Nathalie

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Lecturer University of Montpellier

Contact: nathalie.chevallier(at)umontpellier.fr

Phone: 04 67 14 36 89

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Devau Gina

devau

Neurosciences PhD

Habilitation à Diriger des Recherches

Assistant Professor at the University of Montpellier, France

Contact: gina.devau(at)umontpellier.fr

Phone: 04 67 14 48 30

Team 1: Cerebral aging and neurodegenerative diseases

Presentation 

I carry my teaching and my research in the field of Neurosciences at the Faculty of Science of the University of Montpellier. I am responsible for several Teaching Units in Bachelor and Master. I am interested by the regulatory processes. During my thesis, I have analyzed the effect of serotonin on tyrosine hydroxylase activity of locus coeruleus neurons in culture. Then, in the laboratory Inserm U254 and Inserm 432, I have studied the glutamatergic synaptic transmission in the vestibular and cochlear sensory systems. I have investigated the changes in intracellular calcium induced by activation of glutamate receptors and transporters. Finally, in the MMDN laboratory, Inserm U710 and Inserm 1198, I have explored the gene expression changes during healthy aging and neurodegenerative diseases such as Alzheimer’s disease using transcrptomic approaches, Affymetrix microarrays and RNA-seq. Specific transcriptomic profiles were revealed in relation with age or with the pathology. Some genes were detected highly discriminant to differentiate cerebral aging and the pathology. These studies were funded by the Région Languedoc-Roussillon et interministériel funds "DiaTrAl", National Plan Alzheimer “PRANET“, Européen FP7 "BrainCAV" . I have participated in several meetings organized by Boris Cyrulnik and Antoine Lejeune about resilience process occurring in pathologies associated to aging. I am also implicated to increase public awareness of the progress and benefits of brain research to a large audience. I am in charge on the organization of the Brain Awareness Week in Montpellier, every March. With a local committee, we have created the neurosciences association "La comédie des Neurones".

Lasbleiz Christelle

lasbleiz

Lecturer EPHE

Contact: christelle.lasbleiz(at)umontpellier.fr

Phone: 04 67 14 93 47

Team 1: Cerebral aging and Neurodegenerative diseases

Lebart Marie-Christine

lebart

Lecturer EPHE

Contact: marie-christine.lebart(at)umontpellier.fr

Phone: 04 67 14 39 89

Team 1: Cerebral aging and Neurodegenerative diseases

Lonjon Nicolas

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Clinical Associated University of Montpellier

Contact: n-lonjon(at)chu-montpellier.fr

Team 5: Integrative Biology of Neuroregeneration

Marcilhac Anne

marcilhac

Lecturer EPHE

Contact: marcilhac(at)univ-montp2.fr

Phone: 04 67 14 48 30

Team 1: Cerebral aging and Neurodegenerative diseases

Curriculum-vitae

Marelli Cécilia

marelli

PH CHU

Contact: c-marelli(at)chu-montpellier.fr

Phone: 33 (0)4 67 14 42 70 (Florence Maschat' Units, U1198) / 33(0)4 67 33 60 29 (secretariat CHU, Département de neurologie)

Team 4: Huntington’s disease: Neurophysiopathology from drosophila to mice

Presentation

Cecilia Marelli has been working as Neurologist in the Neurology Department at the Gui de Chauliac University Hospital of Montpellier since October 2010. She is actually completing a PhD degree on P42, a peptide active against Huntington’s disease, under the direction of Florence Maschat (U1198- MMDN)

She completed her residency in neurology at the Istituto Neurologico Besta in Milan (Italy) (in the team "Movement Disorders", directed by the Professor A. Albanese), followed by a one-year fellowship in the same Institute (in the team directed by the Dr D. Pareyson) and by a two –year fellowship in the Genetic Department of the Pitie-Salpetriere Hospital in Paris (in the team Directed by the Professor A. Durr and the Professor A. Brice).

She is mainly interested in the genetic and metabolic aspects of neurodegenerative diseases, notably Huntington’s disease, cerebellar ataxias, spastic paraplegias, and dementias.

Mestre-Francès Nadine

nadine

Study Director EPHE

Contact: nfrances(at)univ-montp2.fr

Phone: 04 67 14 42 52

Team 1: Cerebral aging and Neurodegenerative diseases

PRESENTATION

Nadine Mestre-Frances is an assistant professor at Ecole Pratique des Hautes Etudes. She teachs neuroscience and animal experimentation. She is co-responsible for the team “Cerebral aging and neurodegenerative diseases” in the unit INSERM U1198-EPHE-UM. She studies the Cerebral aging and neurodegenerative diseases such as prion, Alzheimer and Parkinson disease in a non human primate, the gray mouse lemur. The development of this model was supported by various fundings: US Alzheimer organization, France Alzheimer, National Institutes of Health, European Program FP7, GIS Prion, ANR e-rare. Head director of the platform animals models at the Montpellier University (CECEMA, www.cecemaa3l3.univ-montp2.fr)

Perrin Florence

perrin

Professor, University of Montpellier

Contact: florence.perrin(at)umontpellier.fr

Team 5: Integrative Biology of Neuroregeneration

Rossel Mireille

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Assistant Professor EPHE

Contact: mireille.rossel(at)umontpellier.fr / mireille.rossel(at)ephe.sorbonne.fr

Phone: 04 67 14 38 15

Team: Zebrafish Platform, scientific officer

Collaborations:

  • P. Bomont, INM, Montpellier
  • B. Boquet, INM, Montpellier
  • N. Bettache, IBMM, Montpellier
  • C. Paul/ C. Goze, EPHE- Université de Bourgogne
  • TMA Neildez, EPHE-Genethon
  • Pierani Institut Jacques Monod, Paris
  • S. Poluch USUHS Bethesda, US
  • W.Ted. Allison, University of Alberta, Canada

Presentation

After a PhD at the Claude Bernard Lyon1 University, I was interested in pathologies linked to neural crest cells (M. Billaud CNRS lab, Lyon 1993-1995) and then I pursued my research on the early development of the nervous system and its regulation by the Hox genes (M. Capecchi, HHMI, Utah, US, 1995-1999). Recruited at the Ecole Pratique des Hautes Etudes in 2001, my projects focused on the vertebrate nervous system development, and more particularly on factors that regulate neuronal progenitor migrations. In order to analyze the roles of Reelin and CXCL12 chemokine (and its receptors CXCR4/CXCR7), I developed models to study neuronal migration at the level of the hindbrain and neocortex in mice and zebrafish. My current projects aim at identifying the early events involved in the neurotoxicity through zebrafish models.

Scientific event organization: I co-organize the Zebrafish Club, which gather the Montpellier zebrafish community two or three times per year.

I also fulfill administrative functions at the EPHE:  I am a member of the Teaching Board (2012-present) and a member of the Executive Board of the Section of Life Sciences and Earth (2014-present).

Trousse Françoise

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Lecturer EPHE

Contact: francoise.trousse(at)umontpellier.fr / francoise.trousse(at)ephe.sorbonne.fr

Phone: 04 67 14 48 30

Team 1: Vieillissement cérébral et maladies neurodégénératives

Collaborations:

  • Pr. Bovolenta P., CBMSO, CSIC-Universidad Autónoma de Madrid, (CIBERER), Spain

  • Pr. Allard M., Dr. Catheline G., Pr. Micheau J., INCIA, Bordeaux

  • Dr. Bassem Hiba, RMSB, UMR 5536 CNRS/Université de Bordeaux 2

  • Pr. Riedel G., School of Medical Sciences, University of Aberdeen, U.K

Presentation

My research has focused on the development of the nervous system and particularly the role of morphogens in the induction of oligodendrocytes in the chicken neural tube (Ph.D., University Paul Sabatier, P. Cochard, Toulouse, 1998) and in the specification and differentiation vertebrate eye (post-doc, P. Bovolenta, Instituto Cajal-CSIC, Madrid, 1998-2002). Back in Toulouse for a second post-doc (CBD-CNRS, C. Soula, 2003-2006), I studied the function of Glial cell missing gene (Gcm) during vertebrate neurogenesis. In January 2007, I was hired as an Assistant professor at the EPHE, laboratory MMDN. My line of research has focused on the developmental function of an inflammatory protein, Regenerating Islet-1 derived (Reg-1a) expressed early in the central nervous system and found as aggregates in the brain of patients with Alzheimer's disease. Currently my research theme seeks to understand the implication of Reg-1a in neurodegenerative process-related tauopathies from transgenic and cell models.

Verdier Jean-Michel

verdier

MMDN Director, Study Director EPHE

Contact: jean-michel.verdier(at)umontpellier.fr

Phone: 04 67 14 32 91

Team 1: Cerebral aging and Neurodegenerative diseases

Presentation

Biochemist and neurobiologist, J.M. Verdier is a Professor at the École Pratique des Hautes Études (EPHE, Sorbonne, Paris). He leads the lab "Molecular Mechanisms in Neurodegenerative Diseases" (MMDN) of the french National Institute of Health in Montpellier, dedicated to research on the biology of ageing and of neurodegenerative diseases, from cells to humans.

Pr. Verdier’s interests include the development of primate models of neurodegenerative diseases such as Alzheimer and Parkinson diseases, and protein fibril formation in neurodegenerative diseases for which he was awarded the National Academy of Medicine award in 2005.