Former laboratory members

Acquatella Isabelle

acquatella

Postdoctoral Fellow

Contact: iacque(at)univ-montp2.fr

Phone: 04 67 14 33 87

Team 1: Cerebral aging and Neurodegenerative diseases

Akbaraly Tasnime

akbaraly

Research Fellow Inserm

Contact: tasnime.akbaraly(at)inserm.fr

Phone: 04 67 14 36 86

Team 1: Cerebral aging and Neurodegenerative diseases

Team 3: Longevity and vitality

Barbereau Clément

Clment

PhD Student

Contact: clement.barbereau(at)umontpellier.fr

Phone: 04 67 14 38 15

Team: Zebrafish Platform

 

Beluche Isabelle

silhouette f

Engineer Inserm

Contact: isabelle.beluche(at)inserm.fr

Phone: 04 67 14 39 80

Team 3: Longevity and vitality

Presentation

Trained as a biochemist, epidemiologist and statistician.

Involved in 2 projects of the team:

  • European EHLEIS-BRIDGE HEALTH project: Development of an information and dissemination system of life expectancies in Europe (Eurohex),
  • 5-COOP project (France, Switzerland, Denmark, Sweden and Japan): Relationships between the level of mortality selection and the health status of the oldest old.

Bonneaud Nathalie

bonneaud

Research Engineer CNRS

Contact: nathalie.bonneaud(at)umontpellier.fr

Phone: 04 67 14 42 70

Team 4: Huntington’s disease: Neurophysiopathology from drosophila to mice

Curriculum-vitae

Bringuier Claire

Claire

PhD student

Contact: claire.bringuier(at)umontpellier.fr

Team 5: Integrative Biology of Neuroregeneration

 

Canet Geoffrey

PhD Student University of Montpellier

Contact: geoffrey.canet(at)umontpellier.fr

Phone: 04 67 14 38 14

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Célia Hernandez

silhouette f

PhD Student University of Montpellier

Contact: celia.hernandez(at)umontpellier.fr

Phone: 04 67 14 36 89

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Couly Simon

couly

Postdosctoral fellow

Contact: simon.couly(at)inserm.fr

Phone: 04 67 14 32 85

Team 2: "Endogenous neuroprotection in neurodegenerative diseases"

Curriculum-vitae

Cubaynes Sarah

scubaynes

Lecturer, EPHE

Contact: sarah.cubaynes(at)umontpellier.fr / sarah.cubaynes(at)ephe.psi.eu

Phone: 04 67 14 39 80

Team 3: Longevity and Vitality

 

Devau Gina

devau

Neurosciences PhD

Habilitation à Diriger des Recherches

Assistant Professor at the University of Montpellier, France

Contact: gina.devau(at)umontpellier.fr

Phone: 04 67 14 48 30

Group 1: Metabolic impacts in tauopathies

Presentation 

I carry my teaching and my research in the field of Neurosciences at the Faculty of Science of the University of Montpellier. I am responsible for several Teaching Units in Bachelor and Master. I am interested by the regulatory processes. During my thesis, I have analyzed the effect of serotonin on tyrosine hydroxylase activity of locus coeruleus neurons in culture. Then, in the laboratory Inserm U254 and Inserm 432, I have studied the glutamatergic synaptic transmission in the vestibular and cochlear sensory systems. I have investigated the changes in intracellular calcium induced by activation of glutamate receptors and transporters. Finally, in the MMDN laboratory, Inserm U710 and Inserm 1198, I have explored the gene expression changes during healthy aging and neurodegenerative diseases such as Alzheimer’s disease using transcrptomic approaches, Affymetrix microarrays and RNA-seq. Specific transcriptomic profiles were revealed in relation with age or with the pathology. Some genes were detected highly discriminant to differentiate cerebral aging and the pathology. These studies were funded by the Région Languedoc-Roussillon et interministériel funds "DiaTrAl", National Plan Alzheimer “PRANET“, Européen FP7 "BrainCAV" . I have participated in several meetings organized by Boris Cyrulnik and Antoine Lejeune about resilience process occurring in pathologies associated to aging. I am also implicated to increase public awareness of the progress and benefits of brain research to a large audience. I am in charge on the organization of the Brain Awareness Week in Montpellier, every March. With a local committee, we have created the neurosciences association "La comédie des Neurones".

Diez Camille

acquatella

Assistant Engineer

Contact: camille.diez(at)umontpellier.fr

Phone: 04 67 14 36 23

Group 2: Cellular determinants of neuroprotection

Garnier Cyrille

Cyril

Assistant Professor, University of Rennes 1

Contact: cyrille.garnier(at)umontpellier.fr

Phone: 04 67 14 93 47

Team 4: "Huntington’s disease: Neurophysiopathology from drosophila to mice"

Gerber Yannick

perrin

Postdoctoral Fellow University of Montpellier

Contact: yannick.gerber(at)ibn-lab.com

Group 3: Integrative biology of neuroregeneration

Ghysen Alain

ghysen

Research Director Inserm

Contact: alain.ghysen(at)umontpellier.fr

Phone: 04 67 14 32 02

Group 1: Metabolic impacts in tauopathies

Personal Website: http://www.neurodvpmt.univ-montp2.fr/ann4/Alain4.html

Goguadze Nino

goguadze

PhD Student

Contact: nino.goguadze.2(at)iliauni.edu.ge.fr

Phone: 04 67 14 36 23

Team 2 - Group 1: "Endogenous neuroprotection in neurodegenerative diseases"

Huetter Elisabeth

huetter

Technician EPHE

Contact: elisabeth.huetter(at)umontpellier.fr

Phone: 04 67 14 36 89

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Jourdan Christophe

jourdan

Assistant Engineer Inserm

Contact: christophe.jourdan(at)inserm.fr

Phone: 04 67 14 32 85

Team 4: Huntington’s disease: Neurophysiopathology from drosophila to mice

Curriculum-vitae

Lafon Pierre-André

lafon mouton

PhD Student

Contact: pierre.lafon(at)umontpellier.fr

Phone: 04 67 14 33 87

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Lucie Salvador Prince

silhouette f

PhD Student University of Montpellier

Contact: lucie.salvador(at)umontpellier.fr

Phone: 04 67 14 33 87

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Maschat Florence

maschat

Research Director CNRS

Contact: florence.maschat(at)umontpellier.fr

Phone: 33 (0)4 67 14 42 70

Team 4: Huntington’s disease: Neurophysiopathology from drosophila to mice

Collaborations : 

  • Medesis pharma (Private company - Baillargues - France)
  • Pr Michel Vignes (IBMM, University of Montpellier)
  • Pr Edwin Chan (University of Hong Kong)

Resume

Publications

Interview - 2013

Presentation

Our research topics include two axes.

One concerns the study of Engrailed homeoprotein. The identification of the regulatory networks involving this transcription factor have been carried out using genomic scale approaches: chromatin immunoprecipitation experiments to isolate direct targets genes and two-hybrid experiments in yeast to identify Engrailed cofactors. Our team has recently focused on Engrailed implication in neurodevelopment, and the identification of genes regulated by Engrailed and its cofactor (Neuro-Goosberry) to better understand the role of Engrailed in the construction of the nerve cord of an embryo.

On the other hand, among the direct targets of Engrailed, we identified that the Huntingtin, whose human homolog is involved in Huntington's disease (a rare neurodegenerative disease), is directly activated by Engrailed. This allowed us to develop a different axis and identify a 23aa peptide P42 contained in the Huntingtin protein which presents protective properties of this disease in Drosophila but also in mice. Besides obtaining international patents, P42 recently obtained an orphan drug designation by the European Medicines Agency (EMA). We plan to further develop this axis to better understand the physiological role of P42 and the mechanisms of action of this peptide in a view of its development at therapeutic purposes.

Moussaed Mireille

moussaed

PhD Student

Contact: mireillemsaed(at)hotmail.com

Phone: 04 67 14 33 87

Team 1: Cerebral aging and Neurodegenerative diseases

Noristani Harun

perrin

Postdoctoral Fellow University of Montpellier

Contact: harun.noristani(at)ibn-lab.com

Team 5: Integrative Biology of Neuroregeneration

Pascal Eloïse

silhouette f

Ingénieure d'étude

Contact : eloise.pascal(at)umontpellier.fr

Téléphone : 04 67 14 36 89

Group 4 : Environmental impact in Alzheimer's disease and related disorders

Perrier Christine

perrier c

Assistant EPHE

Contact: christine.perrier(at)inserm.fr

Phone: 04 67 14 33 85

Team 3: Longevity and vitality

Perrier Véronique

perrier v

Research Fellow CNRS

Contact: veronique.perrier(at)umontpellier.fr

Phone: 04 67 14 33 87

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Curriculum-vitae

Recent collaborations:

  • Pr Liu J., Huazhong University of Science and Technology, Wuhan, China.
  • Dr. Robitzer M., Institut Charles Gehrard, Laboratoire MACS, Montpellier.
  • Dr. Bougard D., Etablissement Français du Sang, Laboratoire Transdiag, Montpellier.
  • Dr. Prevostel C., Institut de Recherche en Cancérologie de Montpellier, Montpellier.

Presentation

After obtaining my PhD in the field of protein biochemistry at the Pasteur Institute of Paris (1997, Paris XI University, Orsay), I continued my education with a postdoctoral training on the innovative concept of  "prions", which are infectious proteins responsible of prion diseases. I joined the laboratory of Pr. S. Prusiner in the United States (San Francisco, CA, 1997-2000) to study the mecanisms of resistance of prions via the characterization of "dominant negative" polymorphisms in transgenic mice, as well as a new approach of structure-based drug design via molecular and cellular screenings.In 2000, I got a researcher position at the CNRS and I joined the laboratory of Pr. S. Lehmann (Institute of Human Genetics, Montpellier, 2001-2004). The identification of antibodies and molecules such as dendrimers having "anti-prion" properties in cell cultures, and the development of lentiviral vectors carrying "dominant negative" prion proteins to develop a gene therapy approach were the main work carried out during this period.Since 2005, I joined the laboratory INSERM U710-now U1198- headed by Dr. JM Verdier. My research theme focuses on the study of molecular mechanisms involved in neurodegenerative diseases. I identified a family of thienyl pyrimidine compounds that specifically induce oligomers of the pathological isoform of the prion protein, PrPSc. These compounds exhibit very interesting properties for the diagnosis of prions and the deprionization of blood (collaboration with EFS Midi-Pyrénées). Furthermore, one of the identified compounds is a molecule derived from α-tertiophenes, which are synthesized by plants and possessed powerful herbicidal properties. Currently, my research theme has evolved into the role of pesticides in neurodegenerative diseases especially Alzheimer's and prions.

Rouland Sylvie

silhouette f

Technician EPHE

Contact: sylvie.rouland(at)univ-montp2.fr

Phone: 04 67 14 33 87

Team 1: Cerebral aging and Neurodegenerative diseases

Saint Martin Guillaume

perrin

Postdoctoral Fellow University of Montpellier

Contact: gsaintmartin(at)sfr.fr

Team 5: Integrative Biology of Neuroregeneration

Seveno Marie

seveno

Technician University of Montpellier

Team 1: Cerebral aging and Neurodegenerative diseases

Silhol Michèle

silhouette f

Engineer CNRS

Contact: michele.silhol(at)univ-montp2.fr

Phone: 04 67 14 38 15

Team 1: Cerebral aging and Neurodegenerative diseases

Teigell-Webb Marisa

perrin

PhD Student University of Montpellier

Team 5: Integrative Biology of Neuroregeneration

Torrent i Mas Joan

Joan

Research Fellow Inserm

Contact: joan.torrent(at)inserm.fr

Phone: 04 67 14 33 87

Team 6: "Environmental impact in Alzheimer's disease and related disorders"

Trouche Stéphanie

silhouette f

Postdoctoral Fellow EPHE

Contact: stephanie.trouche(at)univ-montp2.fr

Phone: 04 67 14 38 89

Team 1: Cerebral aging and Neurodegenerative diseases

Curriculum-vitae

Yehya A

silhouette f

PhD Student

Team 1: Cerebral aging and Neurodegenerative diseases