2021
Abatematteo FS, Mosier PD, Niso M, Brunetti L, Berardi F, Loiodice F, Contino M, Delprat B, Maurice T, Laghezza A, Abate C. Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effects. Eur J Med Chem. Dec 3, 2021;228:114038.
Barbereau C,Cubedo N,Maurice T,Rossel M. Zebrafish models for studying new pathways in tauopathies.Int J Mol Sci. 2021;22:4626.
Bassani S, van Beelen E,Rossel M, Voisin N, Morgan A, Arribat Y, Chatron N, Chrast J, Cocca M,Delprat B, Faletra F, Giannuzzi G, Guex N, Machavoine R, Pradervand S, Smits JJ, van de Kamp JM, Ziegler A, Amati F, Marlin S, Kremer H, Locher H,Maurice T, Gasparini P, Girotto G, Reymond A. Variants in USP48, which encodes ubiquitin hydrolase, are associated with autosomal dominant non-syndromic hereditary hearing loss. Hum Mol Genet. September 15, 2021;30(19):1785-1796.
Canouï-Poitrine F, Rachas A, Thomas M, Carcaillon-Bentata L, Fontaine R, Gavazzi G, Laurent M,Robine JM. Magnitude, change over time, demographic characteristics, and geographic distribution of excess deaths among nursing home residents during the first wave of COVID-19 in France: a nationwide cohort study.Age Aging. 2021;in press.
Cahu M, Ali LMA, Sene S, Long J, Camerel F, Ciancone M, Salles F, Chopineau J, Devoisselle JM, Felix G, Cubedo N, Rossel M, Guari Y, Bettache N, Larionova J, Gary-Bobo M. A rational study of the influence of Mn2+ insertion in Prussian blue nanoparticles on their photothermal properties. J Mater Chem B. Dec 8, 2021;9(47):9670-9683.
Cecon E, Lhomme T,Maurice T, Luka M, Chen M, Silva A, Wauman J, Zabeau L, Tavernier J, Prévot V, Dam J, Jockers R. The Amyloid Beta Peptide Is an Endogenous Negative Allosteric Modulator of the Leptin Receptor. Neuroendocrinology. 2021;111(4):370-387.
Chevreau R, Ghazale H, Ripoll C, Chalfouh C, Delarue Q, Hemonnot-Girard AL, Mamaeva D, Hirbec H, Rothhut B, Wahane S,Perrin FE, Noristani HN, Guerout N, Hugnot JP. RNA profiling of mouse ependymal cells after spinal cord injury identifies the oncostatin pathway as a potential key regulator of spinal cord stem cell fate. Cells. Nov. 27, 2021;10(12):3332.
Couly S,Carles A,Denus M, Benigno-Anton L,Maschat F,Maurice T. Exposure of R6/2 mice to an enriched environment enhances the efficacy of P42 therapy in slowing the progression of Huntington’s disease.Neuropharmacology. March 15, 2021;186:108467. doi: 10.1016/j.neuropharm.2021.108467
Couly S, Denus M, Bouchet M, RubinstennG, Maurice T. Anti-Amnesic and Neuroprotective Effects of Fluoroethylnormemantine in a Pharmacological Mouse Model of Alzheimer’s Disease. Int J Neuropsychopharmacol. Feb 15, 2021;24(2):142-157.
Crouzier L, Denus M, Richard EM, Tavernier A, Diez C, Cubedo N, Maurice T, Delprat B. The Sigma-1 Receptor Is Critical for Mitochondrial Activity and the Unfolded Protein Response in Larval Zebrafish. Int J Mol Sci. Oct. 13, 2021;22(20):11049.
Crouzier L, Richard EM, Sourbron J, Lagae L, Maurice T, Delprat B. Use of zebrafish models to advance research on rare genetic diseases. Int J Mol Sci. Dec. 12, 2021; 22:13356.
Crouzier L,Diez C, Richard EM,Cubedo N,Barbereau C,Rossel M, Delaunay T,Maurice T,Delprat B. Loss of Pde6a induces rod outer segment shrinkage and visual impairments inpde6aQ70Xmutant zebrafish, a relevant model of retinal dystrophy.Front Cell Dev Biol. 2021
Forner-Piquer I, Klement W, Gangarossa G, Zub E, de Bock F, Blaquiere M,Maurice T, Audinat E, Faucherre A, Lasserre F, Ellero-Simatos S, Gamet-Payrastre L, Jopling C, Marchi N. Varying modalities of perinatal exposure to a pesticide cocktail elicit neurological adaptations in mice and zebrafish. Environ Pollut. June 1, 2021;278:116755.
Garcia J, Torres C, Barbieri M., Cambois E, Camarda CG, Caporali A, Meslé F, Poniakina S,Robine JM. Differences in COVID-19 Mortality: The Implications of Imperfect and Diverse Data Collection Systems.Population-E. 2021;76(1):035–072.
Gautier T, Deckert V, Nguyen M,Desrumaux C, Masson D, Lagrost L. New therapeutic horizons for plasma phospholipid transfer protein (PLTP): Targeting endotoxemia, infection, and sepsis.Pharmacol Ther. Dec. 30, 2021;236:108105.
He F, Chou CJ, Scheiner M, Poeta E, Yuan Chen N, Gunesch S, Hoffmann M, Sotriffer C, Monti B,Maurice T, Decker M. Melatonin- and ferulic acid-based HDAC6 selective inhibitors exhibit pronounced immunomodulatory effects in vitro and neuroprotective effects in a pharmacological Alzheimer’s disease mouse model. J Med Chem. April 8, 2021;64(7):3794-3812.
Hemonnot-Girard AL, Valverde AJ, Hua J, Delaygue C, Linck N,Maurice T, Rassendren F, Hirbec H. Analysis of CX3CR1 haplodeficiency in male and female APPswe/PSEN1dE9 mice as Alzheimer's disease progresses. Brain Behav Immun. Jan. 2021;91:404-417.
Jamoussi Y, Zaiter T,Desrumaux C, Acar N, Pellequer Y, Béduneau A. Investigation of the spontaneous nanoemulsification process with medium- and long-chain triglycerides.Colloids Surf B Biointerfaces. Jan. 2021;197:111432.
Lattard A,Poulen G,Bartolami S,Gerber YN,Perrin FE.Negative impact of Sigma-1 receptor agonist treatment on tissue integrity and motor function following spinal cord injury. Frontiers in Neuroanatomy and Neuropharmacology. 2021, 12:614949.
Legrand A, Pujol C, Durand CM, Mesnil A, Rubera I, Duranton C, Zuily S, Sousa AB, Renaud M, Boucher JL, Pietrancosta N, Adham S, Orssaud C,Marelli C, Casali C, Ziccardi L, Villain N, Ewenczyk C, Durr A, Mignot C, Stevanin G, Billon C, Hureaux M, Jeunemaitre X, Goizet C, Albuisson J. Pseudoxanthoma elasticum overlaps with hereditary spastic paraplegia type 56.J Intern Med. May 2021;289(5):709-725.
Lievens JC, Maurice T. Sigma-1 receptor: culprit and rescuer in motor neuron diseases.Neural Regen Res. Jan. 2021;16(1):106-107.
Maurice T. Biphasic dose response in the preclinical and clinical development of sigma-1 receptor ligands for the treatment of neurodegenerative disorders. Expert Opin Drug Discov. April 2021;16(4):373-389.
Montaut S, Diedhiou N, Fahrer P,Marelli C, Lhermitte B, Robelin L, Vincent MC, Corti L, Taieb G, Gebus O, Rudolf G, Tarabeux J, Dondaine N, Canuet M, Almeras M, Benkirane M, Larrieu L, Chanson JB, Nadaj-Pakleza A, Echaniz-Laguna A, Cauquil C, Lannes B, Chelly J, Anheim M, Puccio H, Tranchant C. Biallelic RFC1 expansion in a French multicenter cohort of sporadic ataxia.J Neurol. March 5, 2021.
Moutin E, Sakkaki S, Compan V, Bouquier N, Giona F, Areias J, Goyet E, Hemonnot-Girard AL, Seube V, Glasson B, Benac N, Chastagnier Y, Raynaud F, Audinat E, Groc L,Maurice T, Sala C, Verpelli C, Perroy J. Restoring glutamate receptosome dynamics at synapses rescues autism-like deficits in Shank3-deficient mice. Mol Psychiatry. 2021
Nakanishi Y, Tsugihashi Y, Akahane M, Noda T, Nishioka Y, Myojin T, Kubo S, Higashino T, Okuda N, Robine JM, Imamura T. Comparison of Medical Expenditures Among Japanese Centenarians and Noncentenarians in the Last Year of Life. JAMA Netw Open. Nov. 1, 2021;4(11):e2131884.
Nasri A, Mezni A, Lafon PA, Wahbi A,Cubedo N, Clair P, Harrath AH, Beyrem H,Rossel M, Perrier V. Ethinylestradiol (EE2) residues from birth control pills impair nervous system development and swimming behavior in zebrafish larvae. Sci Total Environ. May 20, 2021;770:145272.
Patergnani S, Marchi S,Delprat B, Wieckowski MR. Editorial: Organelle Relationships and Interactions: A Cancer Perspective.Front Cell Dev Biol. April 8, 2021;9:678307.
Perez JCP,Gerber YN,Perrin FE(2021). Dynamic diversity of glial response among species in spinal cord injury.Front Aging Neurosci, in press.
Poulen G,Aloy A,Bringuier C,Mestre-Francés N, Artus E, Cardoso M, Perez JC,Goze-Bac C,Lonjon N, Boukhaddaoui H,Gerber YN,Perrin FE. Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates.*Theranostics*, 2021 , 11: 8640–59.
Poulen G,Bartolami S,Noristani HN,Perrin FE,Gerber YN. Unlike brief inhibition of microglia proliferation following spinal cord injury, long-term treatment does not improve motor recovery.Brain Sci. Dec. 13, 2021;11(12):1643.
Poulen G,Gerber YN,Perez JC, Oubarrahou M,Lonjon N, Vachiery-Lahaye F, Boukhaddaoui H, Perrin F. Coherent anti-Stokes Raman scattering microscopy: a label-free method for comparing spinal cord myelin in different species.Front Phys, 9:6656650.
Quijal-Zamorano M, Martinez-Solanas E, Achebak H, Petrova D,Robine JM, Herrmann FR, Rod. X, Ballester J. Reversal of seasonal trends in temperature-attributable mortality projections due to previously unobserved extreme heat in Europe. Lancet Planet Health. September 2021;5(9):e573-e575.
Ravel JM, Benkirane M, Calmels N,Marelli C, Ory-Magne F, Ewenczyk C, Halleb Y, Tison F, Lecocq C, Pische G, Casenave P, Chaussenot A, Frismand S, Tyvaert L, Larrieu L, Pointaux M, Drouot N, Bossenmeyer-Pourié C, Oussalah A, Guéant JL, Leheup B, Bonnet C, Anheim M, Tranchant C, Lambert L, Chelly J, Koenig M, Renaud M. Expanding the clinical spectrum of STIP1 homology and U-box containing protein 1-associated ataxia.J Neurol. May 2021;268(5):1927-1937.
Scheiner M, Hoffmann M, He F, Poeta E, Chatonnet A, Monti B,Maurice T, Decker M. Selective Pseudo-Irreversible Butyrylcholinesterase Inhibitors That Transfer Antioxidant Moieties to the Enzyme Exhibit Pronounced Neuroprotective Efficacy In Vitro and In Vivo in a Mouse Model of Alzheimer’s Disease. J Med Chem. July 8, 2021;64(13):9302-9320.
Verkhratsky A,Dayanithi G. When day meets night: Decreased calcium signaling translates daylight into new neurons.Cell Calcium. May 2021;95:102385.
Wang Y, Lafon PA, Salvador-Prince L, Gines AR,Trousse F, Torrent J, Prevostel C, Crozet C, Liu J, Perrier V. Prenatal exposure to low doses of fungicides impairs neurogenesis in neonates.Environ Res. April 2021;195:110829.